Planning target volume density impact on treatment planning for lung stereotactic body radiation therapy

Savanović, Milovan; Jaroš, Dražan; Foulquier, J.N.

doi:10.1080/0284186x.2021.1950926

Cited by 3 publications

(3 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…If the independent dose verification with DoseCHECK did not clear the tolerance validation, overriding the density around the tumor might be a solution. However, there is a discrepancy between the isodose line obtained by overwriting and the actual isodose line in the lung 33 . The verification using MC algorithm actual dose after density override in lung will be subject to future research.…”

Section: Discussionmentioning

confidence: 99%

“…Savanović et al if the PTV density is less than 0.36 g/cm 3 , it is recommended that the ITV be overridden to 0.8 g/cm 3 to improve and simplify treatment planning without affecting treatment safety. 33 If the independent dose verification with DoseCHECK did not clear the tolerance validation, overriding the density around the tumor might be a solution. However, there is a discrepancy between the isodose line obtained by overwriting and the actual isodose line in the lung.…”

Section: Discussionmentioning

confidence: 99%

“…However, there is a discrepancy between the isodose line obtained by overwriting and the actual isodose line in the lung. 33 The verification using MC algorithm actual dose after density override in lung will be subject to future research.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Dosimetric evaluation in Helical TomoTherapy for lung SBRT using Monte Carlo‐based independent dose verification software

Kosaka,

Takatsu,

Inoue

et al. 2024

J Applied Clin Med Phys

View full text Add to dashboard Cite

PurposeTo elucidate the dosimetric errors caused by a model‐based algorithm in lung stereotactic body radiation therapy (SBRT) with Helical TomoTherapy (HT) using Monte Carlo (MC)‐based dose verification software.MethodsFor 38 plans of lung SBRT, the dose calculation accuracy of a treatment planning system (TPS) of HT was compared with the results of DoseCHECK, the commercial MC‐based independent verification software. The following indices were extracted to evaluate the correlation of dosimetric errors: (1) target volume, (2) average computed tomography (CT) value of the planning target volume (PTV) margin, and (3) average CT value of surrounding 2‐mm area of the PTV (PTV ring). Receiver operating characteristic (ROC) analyses determined the threshold for 5% of differences in PTV D95%. Then, the 38 plans were classified into two groups using the cutoff values of ROC analysis for these three indices. Dosimetric differences between groups were statistically compared using the Mann–Whitney U test.ResultsTPS of HT overestimated by more than 5% in the PTV D95% in 16 of 38 plans. The PTV ring showed the strongest correlation with dosimetric differences. The cutoff value for the target volume, the PTV margin, and the PTV ring was 14.7 cc, −754 HU, and −708 HU, respectively. The area under the curve (AUC) for the target volume, the PTV margin, and the PTV ring were 0.835, 0.878, and 0.932, respectively. Dosimetric errors more than 5% were observed when the PTV volume was less than 15 cc or when the CT value around the target was less than −700 HU.ConclusionThe TPS of HT might overestimate the PTV dose by more than 5% if any the three indices in this study were below threshold. Therefore, independent verification with an MC‐based algorithm should be strongly recommended for lung SBRT in HT.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%