Placental levels of essential and non-essential trace element in relation to neonatal weight in Northwestern Spain: application of generalized additive models

Álvarez-Silvares, Esther; Fernández-Cruz, Tania; Bermúdez-González, Mónica; Rubio-Cid, Paula; Almeida, A.; Pinto, Edgar; Seoane-Pillado, Teresa; Elena, María

doi:10.1007/s11356-023-26560-x

Cited by 5 publications

(1 citation statement)

References 87 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The placenta maintains pregnancy and controls the transfer of gases and nutrients between mother and fetus, which is essential for fetal growth and development [ 70 , 71 ]. Exposure to harmful or toxic elements in preconception during the first trimester can lead to structural alterations when compromised organogenesis [ 71 , 72 ].…”

Section: Reviewmentioning

confidence: 99%

Maternal Exposure to Arsenic and Its Impact on Maternal and Fetal Health: A Review

Ortiz-Garcia,

Cipriano Ramírez,

Juarez

et al. 2023

Cureus

View full text Add to dashboard Cite

Arsenic exposure is a significant public health issue, with harmful effects caused by its use in commercial products such as car batteries, pesticides, and herbicides. Arsenic has three main compounds: inorganic, organic, and arsine gas. Inorganic arsenic compounds in water are highly toxic. The daily intake of arsenic from food and beverages is between 20 and 300 mcg/day. Arsenic is known for its carcinogenic properties and is classified as a human carcinogen by different institutions. Exposure can lead to oxidative stress, DNA damage, and epigenetic deregulation, which can cause endocrine disorders, altered signal transduction pathways, and cell proliferation. In addition, arsenic can easily cross the placenta, making it a critical concern for maternal and fetal health. Exposure can lead to complications such as gestational diabetes, anemia, low birth weight, miscarriage, and congenital anomalies. Female babies are particularly vulnerable to the negative impact of arsenic exposure, with a higher risk of low weight for gestational age and congenital cardiac anomalies. Therefore, it is crucial to monitor and regulate the levels of arsenic in drinking water and food sources to prevent these adverse health outcomes. Further research is necessary to fully understand the impact of arsenic exposure on human health, especially during pregnancy and infancy, by implementing preventative measures and monitoring the levels of arsenic in the environment.

show abstract