Placental insufficiency as the underlying condition of the complications and outcomes of the gestation period

Pestrikova, T Yu; Yurasova, E A; Tkachenko, V. A.

doi:10.17116/rosakush2020200115

Cited by 5 publications

(1 citation statement)

References 13 publications

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“…Вероятность восходящего инфицирования микроорганизмами родового канала возрас тает при преждевременном излитии около плодных вод (ПИОВ) и длительном безвод ном периоде, что способствует возникнове нию внутриутробной пневмонии. Ведущую роль в этом процессе играет трансамниаль ное инфицирование легочной жидкости, что вызывает у новорожденного формирование гиалиновых мембран и развитие дыхатель ной недостаточности [5][6][7].…”

Section: Introductionunclassified

Analysis of congenital pneumonia incidence in newborns from high-risk mothers

Tezikov

Липатов²,

Zagrebelnaya³

et al. 2023

Perm Medical Journal

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Objective. To detect the incidence of congenital pneumonia in newborns from mothers with placental insufficiency in combination with premature amniotic fluid discharge Materials and methods. A retrospective analysis of 57 stories of newborn infants and their mothers was carried out. The newborns were divided into 3 groups: group 1 37 newborns from mothers with placental insufficiency and premature amniotic fluid discharge, group 2 9 infants from mothers with premature amniotic fluid discharge, group 3 11 infants born from mothers with placental insufficiency. The obstetric and gynecological history, the presence of extragenital pathology, the peculiarities of the course of pregnancy and childbirth, and the outcomes for newborns were analyzed. Results. Congenital pneumonia was more common in newborns from mothers with placental insufficiency and premature amniotic fluid discharge. In newborn infants of the first group, severe asphyxia occurred more often, being a risk factor. At the same time, the identification of markers of the systemic inflammatory reaction did not always reflect the presence of infectious-inflammatory pathology in newborns. In addition, in the presence of inflammation of the fetal part of placenta, in a large number of newborns pathological microflora is detected during microbiological examination. Conclusions. As a result of the study, the role of maternal pathology on the development of intrauterine infection and implementation of infection in the early neonatal period was revealed. The obtained data justify the need for pregravid preparation and prevention of perinatal complications in women with placental insufficiency.

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Section: Introductionunclassified