Placental fusion in a dichorionic-diamniotic IVF twin pregnancy – case presentation

Abstract

Twin pregnancies have an increased incidence in recent years, especially due to the development of assisted human reproduction techniques. Although most of the in vitro fertilization pregnancies are dichorionic tasks, exceptions may also occur following the placental fusion process. Twin pregnancies in which the fusion process occurs associate the complications of monochorial pregnancies such as prematurity, growth discordance between the twins, twin-to-twin transfusion syndrome, twin reversed arterial perfusion, with higher perinatal mortality and morbidity. In recent years, most studies have focused on correlations between the macro and microscopic aspects of the placenta and the associated complications.

Potential of DNA zygosity tests for non-invasive evaluation of risk of complications in twin pregnancies

“…Reverse misdiagnoses of DC as MC pregnancies prior to 14 weeks of gestation are also encountered in medical practice [21]. In our study, as much as 10% of pregnancies (4 cases) were misdiagnosed during the early ultrasound scan as high-risk MC gestations, but were found to be DZ by DNA testing, which may be explained as a result of fusion of DZ placentas [22]. These four misdiagnoses were made at two different obstetric units in Gdańsk by different physicians dedicated to obstetric ultrasound and with the use of different equipment, which excludes systematic error of one examiner as explanation of the observed discrepancies.…”