“…As with rubella, infection of the fetus seems to be more likely to occur when the mother is infected early, during the first or second trimester. Nevertheless, the fetus can be infected eyen very late in pregnancy, and Hayes and Gibas (1971) also showed that the fetus may escape infection during the second trimester even when this involves the placenta. In the same way early infection of the fetus is not necessarily followed by obvious brain damage.…”