Placenta Previa Complicated with Endometriosis: Contemporary Clinical Management, Molecular Mechanisms, and Future Research Opportunities

Matsuzaki, Shinya; Nagase, Yoshinori; Ueda, Yutaka; Kakuda, Mamoru; Maeda, Michihide; Kamiura, Shoji

doi:10.3390/biomedicines9111536

Cited by 18 publications

(19 citation statements)

References 114 publications

(303 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The association between endometriosis and an increased risk of placenta previa is robust [ 23 , 24 , 29 , 97 , 98 ]. Notably, placenta previa is the most significant risk factor for PASD [ 15 , 17 , 98 , 99 , 100 , 101 ].…”

Section: Discussionmentioning

confidence: 99%

“…Since endometriotic lesions are difficult to diagnose in pregnant women, the current study identified endometriosis in pregnant women with the following criteria [ 29 ]: (i) histologically confirmed endometriosis; (ii) endometriosis diagnosed by clinical findings (e.g., ultrasound, pelvic adhesions, posterior uterine wall adhesions, or the existence of an endometriotic cyst); (iii) endometriosis suspected clinically or histopathologically during cesarean delivery; and (iv) women identified with endometriosis by using the International Classification of Diseases code. Severe endometriosis was defined as deep infiltrating endometriosis or revised American Society for Reproductive Medicine stage III or IV endometriosis.…”

Section: Methodsmentioning

confidence: 99%

“…A systematic literature search was performed to examine the effect of endometriosis on the incidence of PASD. The same search terms used for endometriosis during our previous systematic review were used during this study ( Supplemental File S1 ) [ 29 ]. The outcomes of interest during this study were as follows: (i) the effect of endometriosis on the prevalence of PASD; (ii) the effect of endometriosis on surgical outcomes of patients with placenta previa and endometriosis; (iii) the effect of ART on the incidence of placenta previa; (iv) the influence of ART on the PASD rate.…”

Section: Methodsmentioning

confidence: 99%

See 2 more Smart Citations

Placenta Accreta Spectrum Disorder Complicated with Endometriosis: Systematic Review and Meta-Analysis

et al. 2022

Self Cite

View full text Add to dashboard Cite

This study aimed to assess the relationship between placenta accreta spectrum disorder (PASD) and endometriosis. The relationships among pregnancy, assisted reproductive technology (ART), placenta previa, ART-conceived pregnancy and PASD were also determined. A systematic literature review was conducted using multiple computerized databases. Forty-eight studies (1990–2021) met the inclusion criteria. According to the adjusted pooled analysis (n = 3), endometriosis was associated with an increased prevalence of PASD (adjusted odds ratio [OR] 3.39, 95% confidence interval [CI] 1.96–5.87). In the included studies, the ART rate ranged from 18.2% to 37.2% for women with endometriosis. According to the adjusted pooled analysis, women who used ART were more likely to have placenta previa (n = 13: adjusted OR 2.96, 95%CI, 2.43–3.60) and PASD (n = 4: adjusted OR 3.54, 95%CI 1.86–6.76) than those who did not use ART. According to the sensitivity analysis using an unadjusted analysis accounting for the type of ART, frozen embryo transfer (ET) was associated with an increased risk of PASD (n = 4: OR 2.79, 95%CI, 1.22−6.37) compared to fresh ET. Endometriosis may be associated with an increased rate of PASD. Women with placenta previa complicated with endometriosis who conceived using frozen ET may be a high risk for PASD.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Placenta Accreta Spectrum Disorder Complicated with Endometriosis: Systematic Review and Meta-Analysis

et al. 2022

Self Cite

View full text Add to dashboard Cite

show abstract

“…Since accurate diagnosis of endometriosis during pregnancy is challenging, endometriosis during pregnancy was defined in this study as previously described [ 21 ]: (i) a past surgical history for endometriosis; (ii) a clinical diagnosis of endometriosis (ultrasonographic findings, pelvic adhesions, PEUA, and ovarian endometrioma); (iii) a clinical or histopathological diagnosis of endometriosis during CD; and (iv) an International Classification of Diseases code registration for endometriosis.…”

Section: Methodsmentioning

confidence: 99%

Association between Endometriosis and Delivery Outcomes: A Systematic Review and Meta-Analysis

et al. 2022

Self Cite

View full text Add to dashboard Cite

Endometriosis is a common benign gynecological disorder; however, delivery outcomes concerning pregnancies with endometriosis remain understudied. This study aimed to assess the effect of endometriosis on delivery outcomes, including the rate of instrumental delivery, cesarean delivery (CD), postpartum hemorrhage (PPH), and perioperative complications during CD. A systematic literature review was conducted using multiple computerized databases, and 28 studies met the inclusion criteria. Pooled analysis showed that histologically diagnosed endometriosis was associated with an increased rate of instrumental delivery (odds ratio [OR] 1.26, 95% confidence interval [CI] 1.02−1.56) and an increased risk of CD (adjusted OR 2.59, 95%CI 1.32−5.07). In our analysis, histologically diagnosed endometriosis was not associated with an increased rate of PPH; however, one retrospective study reported that endometriosis increased the rate of PPH during CD (adjusted OR 1.7, 95%CI 1.5−2.0). Two studies examined perioperative complications during CD, and women with deep endometriosis had a higher rate of bowel resection or bladder injury than those without endometriosis. Our findings suggest that endometriosis is a significant risk factor for instrumental delivery and CD and may be associated with a higher rate of PPH and intraoperative complications during CD.

show abstract

“…In women with PAS, myometrial invasion interferes with placental detachment, leading to significant maternal morbidity [11][12][13][14][15]. Postpartum hemorrhage is a major complication of PAS, and intraoperative blood loss potentially exceeds several liters, possibly leading to shock and coagulopathy [16][17][18][19][20][21][22]. There is a risk of injury to surrounding organs with PAS, particularly to the bladder and ureter.…”

Section: Introductionmentioning

confidence: 99%

Maternal and Fetal Outcomes after Prior Mid-Trimester Uterine Rupture: A Systematic Review with Our Experience

et al. 2021

Self Cite

View full text Add to dashboard Cite

Background and Objectives: Since spontaneous uterine rupture in the mid-trimester is rare, maternal and fetal outcomes in subsequent pregnancies remain unclear. Therefore, this study aimed to examine the maternal and fetal outcomes of subsequent pregnancies after prior mid-trimester uterine rupture. Materials and Methods: A systematic review using PubMed, the Cochrane Central Register of Controlled Trials, and Scopus until 30 September 2021, was conducted in compliance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The studies that clarified the maternal and fetal outcomes after prior mid-trimester uterine rupture and our case (n = 1) were included in the analysis. Results: Among the eligible cases, there were five women with eight subsequent pregnancies after prior mid-trimester uterine rupture. The timing of prior mid-trimester uterine rupture ranged from 15 to 26 weeks of gestation. The gestational age at delivery in subsequent pregnancies was 23–38 gestational weeks. Among the included cases (n = 8), those involving prior mid-trimester uterine rupture appeared to be associated with an increased prevalence of placenta accreta spectrum (PAS) (n = 3, 37.5%) compared with those involving term uterine rupture published in the literature; moreover, one case exhibited recurrent uterine rupture at 23 weeks of gestation (12.5%). No maternal deaths have been reported in subsequent pregnancies following prior mid-trimester uterine rupture. Fetal outcomes were feasible, except for one pregnancy with recurrent mid-trimester uterine rupture at 23 weeks of gestation, whose fetus was alive complicated by cerebral palsy. Conclusions: Our findings suggest that clinicians should be aware of the possibility of PAS and possible uterine rupture in pregnancies after prior mid-trimester uterine rupture. Further case studies are warranted to assess maternal and fetal outcomes in pregnancies following prior mid-trimester prior uterine rupture.

show abstract

Placenta Previa Complicated with Endometriosis: Contemporary Clinical Management, Molecular Mechanisms, and Future Research Opportunities

Cited by 18 publications

References 114 publications

Placenta Accreta Spectrum Disorder Complicated with Endometriosis: Systematic Review and Meta-Analysis

Placenta Accreta Spectrum Disorder Complicated with Endometriosis: Systematic Review and Meta-Analysis

Association between Endometriosis and Delivery Outcomes: A Systematic Review and Meta-Analysis

Maternal and Fetal Outcomes after Prior Mid-Trimester Uterine Rupture: A Systematic Review with Our Experience

Contact Info

Product

Resources

About