Placebo Effect: The Stem of Seminal Studies with Active Treatment Neurobiological Mechanisms, And Implications for Parkinson’s Disease with Deep Brain Stimulation
Thanapat Jitvootthikai
Abstract:Despite long standing controversies about the therapeutic validity of placebo due to its administration of inert substances, placebo emerges for its efficacy to amplify the therapeutic benefits of active medical interventions through patients’ psychological beliefs and expectations. Advances in neuroimaging and utilization of hormonal agonists have elucidated underlying brain mechanisms and biochemical pathways such as the endogenous opioid systems. This research synthesizes pivotal studies on placebo effect, … Show more
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