Placebo-Controlled Study of Lisinopril in Congestive Heart Failure

Chalmers, John; West, Malcolm; Cyran, J.; Torre, Diego de la; Englert, Marc; Kramar, Marija; Lewis, G. R. J.; Maranhao, M. F. L.; Myburgh, D. P.; Schuster, Peter; Sialer, Salvador; Simon, Hermann; Stephens, John D.; Watson, R.

doi:10.1097/00005344-198700003-00021

Cited by 82 publications

(10 citation statements)

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“…148,149 Patients with mild HF respond favorably to low doses because they absorb diuretics rapidly from the bowel and deliver these drugs rapidly to the renal tubules. However, as HF advances, the absorption of the drug may be delayed by bowel edema or intestinal hypoperfusion, and the delivery of the drug and the response to a given intratubular concentration may be impaired by a decline in renal perfusion and function.…”

Section: Effect Of Diuretics In the Management Of Hfmentioning

confidence: 99%

“…Analysis of this collective experience indicates that ACEIs can alleviate symptoms, improve clinical status, and enhance the overall sense of well-being of patients with HF. 145,[147][148][149][150][151][152][153][154][155][156][157] In addition, ACEIs can reduce the risk of death and the combined risk of death or hospitalization. [155][156][157] These benefits of ACE inhibition were seen in patients with mild, moderate, or severe symptoms and in patients with or without coronary artery disease.…”

Section: Angiotensin Converting Enzyme Inhibitors In the Management Omentioning

confidence: 99%

See 1 more Smart Citation

2009 Focused Update Incorporated Into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults

Hunt¹,

Abraham²,

Chin³

et al. 2009

Circulation

1,913

757

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Section: Effect Of Diuretics In the Management Of Hfmentioning

confidence: 99%

Section: Angiotensin Converting Enzyme Inhibitors In the Management Omentioning

confidence: 99%

2009 Focused Update Incorporated Into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults

Hunt¹,

Abraham²,

Chin³

et al. 2009

Circulation

1,913

757

View full text Add to dashboard Cite

“…Analysis of this collective experience indicates that ACEIs can alleviate symptoms, improve clinical status, and enhance the overall sense of well-being of patients with HF (184)(185)(186)(187)(188)(189)(190)(191)(192)(193)(194)(195). In addition, ACEIs can reduce the risk of death and the combined risk of death or hospitalization (193)(194)(195).…”

Section: Practical Use Of Ace Inhibitors Initiation and Maintenancementioning

confidence: 99%

ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult

Hunt

Abraham

Chin³

et al. 2005

Circulation

1,960

773

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“…Lisinopril effectively lowers blood pressure in patients with essential (Bolzano et al, 1987;Morlin etal., 1987;Pool etal., 1987;Zachariah et al, 1987) and renovascular (Donohoe et al, 1987;Fyhrquist et al, 1987) hypertension, and improves signs and symptoms in congestive heart failure (Chalmers et al, 1987;Powers et al, 1987). Clinical experience to date indicates that lisinopril is safe and well tolerated (Rush & Merrill, 1987).…”

Section: Introductionmentioning

confidence: 99%

Lisinopril dose‐response relationship in essential hypertension.

Gómez

Cirillo

Sromovsky

et al. 1989

Brit J Clinical Pharma

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1 This was a multicentre, double-blind, parallel study in 216 patients with mild to moderate (supine diastolic blood pressure = 95-115 mm Hg) essential hypertension. 2 After a 4-week placebo washout, patients were randomized to placebo or lisinopril 1.25, 5, 20 or 80 mg once daily for 6 consecutive weeks. Supine and erect blood pressure was measured 24 h postdose at the end of weeks -2, 0, 2, 4, and 6. 3 There was a linear dose-response relationship for both supine and erect blood pressure. Diastolic blood pressure reductions in the lisinopril 20 and 80 mg day-' groups were significantly greater than in the placebo or lisinopril 1.25 and 5 mg day-' groups. 4 Lisinopril, at doses up to 80 mg day-', was well tolerated.

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Placebo-Controlled Study of Lisinopril in Congestive Heart Failure

Cited by 82 publications

References 0 publications

2009 Focused Update Incorporated Into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults

2009 Focused Update Incorporated Into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults

ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult

Lisinopril dose‐response relationship in essential hypertension.

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