Bariatric surgery (BS) is the most effective intervention for obesity, with proven significant weight loss, complications prevention, comorbidity remission, and improved survival. However, a substantial proportion of patients experience weight loss failure after BS. This review aims to provide an updated insight into weight loss failure after BS, define it, identify its prevalence, explain its health impact, determine risk factors, and summarize prevention and treatment. Future directives and larger-scale prospective studies should be considered to define weight regain (WR) and insufficient weight loss post bariatric surgery and address measures to resolve gaps and controversies.