Place recognition and heading retrieval are dissociable in mice (and possibly men)

Julian, Joshua B.; Keinath, Alexander; Muzzio, Isabel A.; Epstein, Russell A.

doi:10.1167/14.10.364

Journal of Vision

2014

DOI: 10.1167/14.10.364

|View full text |Cite

Place recognition and heading retrieval are dissociable in mice (and possibly men)

Joshua B. Julian

Alexander Keinath

Isabel A. Muzzio

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2015

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These findings suggest selective impairment to representation of geometric layout in people with WS, but not to representation of features, a pattern which is consistent with theories and evidence suggesting that the two navigational systems are separable in terms of both behavioral mechanism (Julian, Keinath, Muzzio, & Epstein, 2014; Lee & Spelke, 2010; Lee, Shusterman, & Spelke, 2006) and underlying neural instantiation (Doeller & Burgess, 2008; Doeller et al, 2008). The WS pattern differs qualitatively from that of TD individuals, for whom geometry is used from a very early point in development, and features are integrated with geometry in both small and large spaces from about age 5 onward (Hermer-Vasquez, Moffet, & Munkholm, 2001; Learmonth et al, 2002).…”

supporting

confidence: 87%

Geometric and featural systems, separable and combined: Evidence from reorientation in people with Williams syndrome

Ferrara

Landau

2015

Cognition

View full text Add to dashboard Cite

Spatial reorientation by humans and other animals engages geometric representations of surface layouts as well as featural landmarks; however, the two types of information are thought to be behaviorally and neurally separable. In this paper, we examine the use of these two types of information during reorientation among children and adults with Williams syndrome (WS), a genetic disorder accompanied by abnormalities in brain regions that support use of both geometry and landmarks. Previous studies of reorientation in adolescents and adults with WS have shown deficits in the ability to use geometry for reorientation, but intact ability to use features, suggesting that the two systems can be differentially impaired by genetic disorder. Using a slightly modified layout, we found that many WS participants could use geometry, and most could use features along with geometry. However, the developmental trajectories for the two systems were quite different from one other, and different from those found in typical development. Purely geometric responding was not correlated with age in WS, and search processes appeared similar to those in typically developing (TD) children. In contrast, use of features in combination with geometry was correlated with age in WS, and search processes were distinctly different from TD children. The results support the view that use of geometry and features stem from different underlying mechanisms, that the developmental trajectories and operation of each are altered in WS, and that combination of information from the two systems is atypical. Given brain abnormalities in regions supporting the two kinds of information, our findings suggest that the co-operation of the two systems is functionally altered in this genetic syndrome.

show abstract

supporting

confidence: 87%

Geometric and featural systems, separable and combined: Evidence from reorientation in people with Williams syndrome

Ferrara

Landau

2015

Cognition

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Place recognition and heading retrieval are dissociable in mice (and possibly men)

Cited by 1 publication

References 0 publications

Geometric and featural systems, separable and combined: Evidence from reorientation in people with Williams syndrome

Geometric and featural systems, separable and combined: Evidence from reorientation in people with Williams syndrome

Contact Info

Product

Resources

About