Place of Cryosurgery in the Treatment of Malignant Liver Tumors

Adam, René; Akpınar, Ersin; Johann, M; Kunstlinger, F; Majno, Pietro; Bismuth, H

doi:10.1097/00000658-199701000-00005

Cited by 255 publications

(132 citation statements)

References 27 publications

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“…A tumour diameter of 30mm or greater and close proximity to major vascular structures are both well documented risk factors for tumour recurrence (6)(7)(8)(9)(10)(11)(12)(13). It is possible that the larger size of one of these tumours may be connected to its recurrence though many larger lesions were successfully treated in this series.…”

Section: A C C E P T E D Article In Pressmentioning

confidence: 85%

Microwave ablation for unresectable hepatic tumours: Clinical results using a novel microwave probe and generator

Bhardwaj

Strickland

Ahmad

et al. 2010

European Journal of Surgical Oncology (EJSO)

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Section: A C C E P T E D Article In Pressmentioning

confidence: 85%

Microwave ablation for unresectable hepatic tumours: Clinical results using a novel microwave probe and generator

Bhardwaj

Strickland

Ahmad

et al. 2010

European Journal of Surgical Oncology (EJSO)

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“…Early reported series of hepatic cryosurgery for colorectal hepatic metastases suggest that this technique is both feasible and safe. [108][109][110] These results, however, are too preliminary to draw conclusions about long-term efficacy. Ravikumar et al 108 reported no deaths in the first 25 patients treated at the New England Deaconess Hospital.…”

Section: Cryosurgery and Other Forms Of Local Hepatic Ablative Therapymentioning

confidence: 88%

“…The efficacy of cryosurgery may depend on the tumor type and the ability to achieve complete freezing of the lesion, with adequate margins. Adam et al 110 reported on 34 patients undergoing cryosurgery for hepatic malignancies, either alone or in combination with resection. Although they found no differences in survival between groups, local recurrence was significantly greater in patients with metastatic colorectal cancer compared with patients with primary liver cancer.…”

Section: Cryosurgery and Other Forms Of Local Hepatic Ablative Therapymentioning

confidence: 99%

Management of hepatic metastases

Choti

Bulkley

1999

Liver Transpl

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Although the liver is the most common site of metastatic disease from a variety of tumor types, isolated hepatic metastases most commonly occur from colorectal cancer and, less frequently, from neuroendocrine tumors, gastrointestinal sarcoma, ocular melanoma, and others. Complete evaluation of the extent of metastatic disease, both intrahepatically and extrahepatically, is important before considering treatment options. Based on a preponderance of uncontrolled studies for hepatic metastatic colorectal carcinoma, surgical resection offers the only potential for cure of selected patients with completely resected disease, with 5-year survival rates of 25% to 46%. Systemic and hepatic arterial infusion chemotherapy may be useful treatment options in patients with unresectable disease and possibly as an adjuvant treatment after liver resection. Other techniques of local tumor ablation, including cryotherapy and radiofrequency ablation, although promising, remain unproved. Management of hepatic metastases from neuroendocrine tumors and other noncolorectal primary tumors should be individualized based on the patient's clinical course, extent of disease, and symptoms. Copyright 1999 by the American Association for the Study of Liver DiseasesA s many as 50% of the patients with a primary malignancy will eventually develop metastases in the liver, a percentage greater than for any other organ, including the lung. Although primary tumors that drain principally into the portal circulation are more likely than others to develop hepatic metastases, many tumors arising in other sites, such as the breast and lung, also commonly develop hepatic metastases. Although the liver represents a common site of spread from many of these solid tumors, isolated hepatic metastases most commonly occur from colorectal and neuroendocrine tumors. Other less common malignancies also can metastasize predominantly to the liver. For most other solid malignancies, the pattern of metastatic disease is most often that of generalized dissemination. Colorectal MetastasesCancer of the colon and rectum is the third most commonly diagnosed cancer in the United States. An estimated 131,600 new cases will have been discovered in 1998, comprising 11% of new cancer diagnoses. 1 An estimated 56,500 deaths will occur from colorectal cancer that year, comprising 10% of all cancer deaths. 1 Although mortality from largebowel cancer has been improving over the past 30 years, largely because of improvements in early detection, diagnosis, and treatment, approximately 50% of the patients with colorectal cancer eventually die of their neoplastic disease. 1 The liver is the most commonly involved organ in patients with metastatic colorectal cancer. Approximately 20% of these patients have clinically recognizable liver metastases at the time of their primary diagnosis. 1,2 After resection of a primary colorectal cancer in the absence of apparent metastatic disease, approximately 50% of the patients will subsequently manifest metastatic liver disease. Given these figures,...

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“…los tumores hepáticos. Esto incluye oclusión de vena porta 5,7,8 , quimioterapia neoadyuvante arterial 9,10 , inmuno-quimio terapia transarterial 11 , y destrucción tumoral local 12,13 .…”

Section: Discussionunclassified

Asociación De La Partición Hepática Y Ligadura De La Vena Portal Para Hepatectomía Por Etapas, Un Nuevo Procedimiento en Cirugía Hepática

Núñez

et al. 2015

Rev Chil Cir

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associating liver partition and portal vein ligation for staged hepatectomy, a new hepatic procedure introduction: Hepatic resection is the standard treatment for the liver tumors and in most cases the only potentially curative option. The most feared complication, in the major hepatic resection, is the postoperative liver failure. A new technique has recently been published in the literature: Liver partition associated to a portal vein ligation for staged hepatectomy. This technique allows an accelerated hipertrophy of the remnant liver, facilitates greater resection surgery, reducing the risk of postoperative hepatic ischemia. The results reported in the literature are promising. We report the first case in Chile with its evolution to 2 years and a discussion about the topic.

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Place of Cryosurgery in the Treatment of Malignant Liver Tumors

Cited by 255 publications

References 27 publications

Microwave ablation for unresectable hepatic tumours: Clinical results using a novel microwave probe and generator

Microwave ablation for unresectable hepatic tumours: Clinical results using a novel microwave probe and generator

Management of hepatic metastases

Asociación De La Partición Hepática Y Ligadura De La Vena Portal Para Hepatectomía Por Etapas, Un Nuevo Procedimiento en Cirugía Hepática

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