2010
DOI: 10.1111/j.1365-4632.2008.03915.x
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Pityriasis lichenoides et varioliformis acuta: a disease spectrum

Abstract: Pityriasis lichenoides et varioliformis acuta (PLEVA), or Mucha-Habermann disease (MHD), is a cutaneous disorder evident with crops of erythematous macules and papules, usually on the trunk and flexural areas of the extremities. Its etiology remains unknown. PLEVA is speculated to be an inflammatory reaction triggered by certain infectious agents, an inflammatory response secondary to T-cell dyscrasia, or an immune complex-mediated hypersensitivity. Histologic examination of a skin biopsy specimen is the stand… Show more

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Cited by 60 publications
(88 citation statements)
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References 35 publications
(107 reference statements)
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“…Finally, there exists reasonable evidence that pityriasis rosea Gibert [95,96] and pityriasis lichenoides et varioliformis acuta Mucha-Habermann [97] are not associated with Mycoplasma infections.…”
Section: Resultsmentioning
confidence: 99%
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“…Finally, there exists reasonable evidence that pityriasis rosea Gibert [95,96] and pityriasis lichenoides et varioliformis acuta Mucha-Habermann [97] are not associated with Mycoplasma infections.…”
Section: Resultsmentioning
confidence: 99%
“…Using the described strategy, 94 reports were retained for the final analysis [4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56,57,58,59,60,61,62,63,64,65,66,67,68,69,70,71,72,73,74,75,76,77,78,79,80,81,82,83,84,85,86,87,88,89,90,91,92,93,94,95,96,97]: 1 in German [23], 1 in Italian […”
Section: Data Assessmentmentioning
confidence: 99%
“…3 aylık tedavi sonrası lezyonlar postlezyonel hiperpigmentasyon ve yer yer atrofik skarlar bırakarak geriledi. Hastalığın etyolojisi tam olarak bilinmemekle birlikte enfeksiyon ajanları tarafından tetiklenen inflamatuar bir reaksiyon, T hücre diskrazisine sekonder gelişen inflamatuar bir yanıt veya immun kompleks aracılı bir hipersensitivite reaksiyonu olabileceği gibi teoriler öne sürülmektedir (5). PLEVA'ya sebep olabilecek ajanlar arasında adenovirüsler, Ebstein-Barr Virus, Toxoplasma gondii, Parvovirus B19, Staphylococcus aureus ve Streptococcus pyogenes yer almaktadır (2).…”
Section: Olguunclassified
“…Klinik olarak en sık karışan hastalık olan lenfomatoid papülozda büyük CD30+ atipik lenfoid hücrelerin olması önemli bir ayırt edici bulgudur. Diğer farkları, Reed-Sternberg hücrelerine benzeyen büyük, atipik, nonlenfoid hücrelerin ve çok sayıda nötrofilin varlığı, nekrotik keratinositlerin az olması veya hiç olmaması, bazal tabakada vakuolar dejenerasyonun az olması veya hiç olmamasıdır (5,6,8).…”
Section: Olguunclassified
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