Pituitary microadenomas: Surgical results and morphological findings

Scanarini, M.; Mingrino, S; Boscaro, Marco; Sicolo, Nicola; Serafini, E.; Billeci, Domenico

doi:10.1007/bf01401810

Cited by 2 publications

(1 citation statement)

References 12 publications

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“…Pituitary adenomas (PA) are intracranial tumours that may result in death [1]. Autopsy studies suggest that microadenomas(<10mm) occur in 10 to 20% of the population [2,3], while macroadenomas >10 mm are quite rare [4,5]. PA commonly produce ocular, or endocrine Case Report symptoms [6], others symptoms relate to mass effect as well as obstruction to cerebrospinal fluid(CSF) flow.Giant PA >/=4cm have been reported [7][8][9][10].…”

Section: Introductionmentioning

confidence: 99%

Death from Neglected Pituitary Adenoma: A Case Report

Ebughe

Ugbem

2019

IJTDH

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We present a case of a patient who presented with pituitary macroadenoma complicated with hydochephalus. He presented late to the referral hospital in a comatose state and died a few hours later. He was a 33-year-old, male who gave a history of highly accelerated symptoms lasting 1 week. Neurosurgical consultation as well as investigations with CT scan or MRI were not availed the patient,which could have been life saving. Autopsy findings were of a pituitary macroadenoma and signs of hydrocephalus and raised intracranial pressure which proved fatal.

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Section: Introductionmentioning

confidence: 99%

Death from Neglected Pituitary Adenoma: A Case Report

Ebughe

Ugbem

2019

IJTDH

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Results of surgical management of 319 pituitary adenomas

1987

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Of the 510 patients with pituitary adenoma treated surgically at our hospital in the period 1956-1984 319 were treated by the microsurgical technique, in the period 1973-1984, 235 by transsphenoidal approach and 84 by subfrontal-pterional approach. The transsphenoidal route was used almost exclusively in microadenomas, in intrasellar adenomas, in suprasellar adenomas with midline development, in adenomas invading the sphenoidal sinus and in haemorrhagic adenomas with considerable suprasellar development. In some giant adenomas the transsphenoidal route was used in a first stage operation for debulking the tumour, later removed by transcranial route. The latter route was preferred in large adenomas and especially in adenomas with laterosellar development. In some patients with PRL secreting adenomas post-operative treatment with bromocriptine proved useful when the hormone levels failed to normalize. Post-operative radiotherapy was of value in invasive adenomas and in cases in which tumour removal was not radical.

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Pituitary microadenomas: Surgical results and morphological findings

Abstract: The results of transsphenoidal microsurgery in treating 22 patients with pituitary microadenomas are reported. Histological and ultrastructural comparative studies were performed in attempting to obtain a more accurate morphological classification of pituitary microadenomas.

Cited by 2 publications

References 12 publications

Death from Neglected Pituitary Adenoma: A Case Report

Death from Neglected Pituitary Adenoma: A Case Report

Results of surgical management of 319 pituitary adenomas

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