Pituitary adenoma associated with craniopharyngioma

Collision lesions of the sella: co-existence of craniopharyngioma with gonadotroph adenoma and of Rathke’s cleft cyst with corticotroph adenoma

“…Estrogen administration is a recognized cause [42,43]. The fourth of the six cases involved a chromophobic adenoma in a patient with clinical manifestations of acromegaly [12]. In addition to these six cases, we encountered two interesting case reports of children with clinical and biochemical Cushing syndrome and a tumor with a cystic or mixed signal suprasellar component [44,45].…”

“…A review of the literature reveals six such cases [11][12][13][14][15][16]. Immunohistochemical studies had been performed in three instances, all of which confirmed a diagnosis of prolactinoma.…”

“…The co-existence of craniopharyngioma and pituitary adenoma has rarely been reported [11][12][13][14][15]. Most remarkable is: (a) triple collision of an adenoma, craniopharyngioma and chordoma in the sellar region [16], (b) a germinoma followed four years later by a craniopharyngioma [17], (c) a contiguous intrasellar chordoma with a suprasellar craniopharyngioma [18] and (d) a cystic astrocytoma of the temporal lobe with a craniopharyngioma [19].…”

Collision Tumors of the Sella: Craniopharyngioma and Silent Pituitary Adenoma Subtype 3: Case Report

“…An exhaustive search of the literature revealed only eight previously reported cases [6][7][8][9][10][11][12][13]. Their clinicopathologic features are summarized in Table 1.…”

“…The eight published cases all involved an adamantinomatous [6][7][8][9][10][11][12][13] craniopharyngioma. Among the pituitary adenomas were five PRL cell adenomas [6-8, 12, 13], including two microadenomas [6,8], one acromegalyassociated GH adenoma [10], one LH/FSH cell adenoma [9], and adenoma not otherwise classified [11].…”