Pituitary abscesses

Domingue, James N.; Wilson, Charles B.

doi:10.3171/jns.1977.46.5.0601

Cited by 110 publications

(12 citation statements)

References 13 publications

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“…The clinical courses, neuroradiological findings and the follow-up ob¬ servations exclude cerebrovascular catastrophes as well as primary and secondary tumours of the pituitary gland and their complications like pitui¬ tary apoplexy and pituitary abscess (Mohr 1975;Domingue & Wilson 1977;Pelkonen et al 1978). Nor was there any history of skull trauma.…”

Section: Discussionmentioning

confidence: 97%

Post-encephalitic hypothalamic-pituitary insufficiency

Kupari

Pelkonen

Valtonen

1980

Acta Endocrinologica

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Pituitary function was investigated in 3 patients who developed hypothalamic-pituitary insufficiency after viral meningoencephalitis. In 2 patients the causative agents were probably Influenza-A-and Herpes simplex virus whereas in the third patient it was not identified. The pattern of hormonal deficiencies indicated that all the central regulatory areas -hypothalamus, pituitary stalk and pituitary gland -may be injured after viral meningoencephalitis. Usually, the hormonal deficiency is permanent but it can also be transient.

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Section: Discussionmentioning

confidence: 97%

Post-encephalitic hypothalamic-pituitary insufficiency

Kupari

Pelkonen

Valtonen

1980

Acta Endocrinologica

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“…Transsphenoidal surgery is considered to be the preferred approach, because it provides a line for prolonged drainage from the infected area, decompression of the optic chiasma, and management of an associated sinusitis if present. [1–412–1421] We used an endoscopic endonasal transsphenoidal approach to treat pituitary abscess. This approach permitted a direct look into surgical anatomy, and gave better magnification and visualization of the hidden zone using a 30° or 70° angled scope.…”

Section: Discussionmentioning

confidence: 99%

Abscess formation associated with pituitary adenoma: A case report: Changes in the MRI appearance of pituitary adenoma before and after abscess formation

Kuge

Sato²,

Takemura³

et al. 2011

Surg Neurol Int

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Background:Pituitary abscess is an extremely rare finding. The abscess may arise as a primary pituitary lesion or be associated with parasellar pathology. It is important for pituitary abscess treatments to perform early diagnosis. In this report, we describe a case of pituitary adenoma in which MRI findings changed during the follow-up period and strongly suggested progression to pituitary abscess arising from adenoma.Case Description:In a 73-year-old female, pituitary adenoma had been incidentally detected; MRI showed typical findings of pituitary adenoma, and we had followed up the pituitary lesion and clinical symptoms. Six months later, she had oculomotor nerve palsy and symptoms of hypopituitarism. Hematological examination revealed inflammation and hypopituitarism. MRI showed striking changes in the signal intensity of the pituitary lesion, and strongly suggested occurrence of sinusitis and pituitary abscess ascribed to pituitary adenoma. She was admitted and endoscopic transsphenoidal surgery was performed. The sellar floor was destroyed, and yellowish-white creamy pus was observed. A histopathological study using hematoxylin-eosin staining showed adenoma and inflammatory cells. Aerobic, anaerobic, and fungal cultures were negative. Antibiotics were administered and hormonal replacement was started. Neurological and general symptoms were improved, and postoperative MRI revealed complete evacuation of abscess and removal of tumor.Conclusions:Pituitary abscess within invasive pituitary adenoma is a rare entity, and shows high mortality. Early diagnosis of pituitary abscess is very important for the prompt surgery and initiation of treatment with antibiotics. In our case, changes in MRI findings were helpful to diagnose pituitary abscess, and endoscopic transsphenoidal surgery was an optimal surgical treatment.

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“…Visual disorders, such as hemianopsia, are also commonly observed. In one series14 57% of patients with PA presented with visual disorders. Central diabetes insipidus has an incidence of 41.4%–69.7% among PA patients 4,7.…”

Section: Discussionmentioning

confidence: 94%

Pituitary abscess: report of two cases and review of the literature

Liu¹,

Liu²,

Qi³

et al. 2017

NDT

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Pituitary abscess is a rare but critical disorder caused by an infectious process where purulent material accumulates inside the sella turcica. Since symptoms, signs and radiographic characteristics of pituitary abscess are similar to several other pituitary lesions, correct diagnosis before surgery is challenging. In this article, two cases of pituitary abscess treated in our department are reported, followed by a literature review. In these two cases, both patients presented with intermittent fever. Magnetic resonance imaging revealed a suprasellar lesion with rim enhancement after contrast injection. After transsphenoidal surgery, the diagnosis of pituitary abscess was confirmed. The patients were then given antibiotic treatment and recovered fully in less than 2 months. Findings of this article support timely diagnosis and proper treatment including transsphenoidal surgery and antibiotic therapy for pituitary abscess, leading to lower mortality rates and higher probability of pituitary hormone function recovery.

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Pituitary abscesses

Cited by 110 publications

References 13 publications

Post-encephalitic hypothalamic-pituitary insufficiency

Post-encephalitic hypothalamic-pituitary insufficiency

Abscess formation associated with pituitary adenoma: A case report: Changes in the MRI appearance of pituitary adenoma before and after abscess formation

Pituitary abscess: report of two cases and review of the literature

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