Pituitary abscess presenting with cranial nerve paresis. Case report and review of literature

Somali, Maria; Anastasiou, Athanasia; Goulis, Dimitrios G.; Polyzoides, C.; Avramides, A.

doi:10.1007/bf03343808

Cited by 9 publications

(2 citation statements)

References 38 publications

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“…Vates et al reported 24 cases drawn from a series of more than 3500 patients who underwent pituitary surgery [2]. [3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22], and a summary of these cases, which we selected for analysis, has been tabulated in Table 2, 3 and 4.…”

Section: Discussionmentioning

confidence: 99%

Pituitary abscess: our experience with a case and a review of the literature

Dalan

Leow

2007

Pituitary

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Pituitary abscess is a rare disease. Due to its potentially high mortality and morbidity rate, it should be considered in the differential diagnosis of sellar masses. Despite recent advances in radiological investigations, making a definitive diagnosis preoperatively remains challenging. This 45-year-old Indian gentleman presented with severe throbbing headache for six months. Magnetic resonance imaging of the brain revealed a sellar mass with peripheral enhancement that was misdiagnosed as a pituitary macroadenoma. A trans-sphenoidal excision was done, which surprisingly yielded only pus that was drained accordingly from the lesion. Fungal and bacterial cultures were negative. However this patient subsequently lost complete function of the pituitary gland, resulting in central diabetes insipidus and required permanent hormonal replacement therapy in the deficient endocrine axes. A Medline search was conducted and a review of 24 cases reported in the last 5 years discussed.

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Section: Discussionmentioning

confidence: 99%

Pituitary abscess: our experience with a case and a review of the literature

Dalan

Leow

2007

Pituitary

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“…An acute sinus infection spreading to the pituitary region has been documented as a cause for pituitary abscess formation, and it is often a result of direct extension from the sphenoid sinus. 4 5 6 …”

Section: Introductionmentioning

confidence: 99%

Pituitary Abscess: A Rare Clinical Entity in the Presence of Acute Rhinosinusitis: A Case Report

2018

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A pituitary abscess is an often-overlooked diagnosis in the clinical presentation of a sellar mass. Due to its rare incidence and nonspecific presentation, diagnosis and treatment is often delayed. The authors describe a 56-year-old male patient presenting with acute onset of severe headache, visual field deficit, and radiologic findings of an expansile sellar lesion. The presenting symptoms were unremarkable for the diagnosis of meningitis, cavernous sinus thrombosis, and septicemia. Recent medical history included symptoms of rhinosinusitis on the days preceding his acute presentation. The initial clinical presentation was suggestive of a possible pituitary apoplexy. Intraoperative findings revealed purulent output upon surgical entry of the sella. Histopathology confirmed the diagnosis of a pituitary abscess. Review of the clinical and radiologic data revealed evidence of multiple opacifications within the paranasal sinuses, along with dehiscence overlying the sellar bone, supporting a diagnosis of secondary pituitary abscess. This case, along with a review of the available literature, will serve to expand our knowledge of this rare disease process that is often overlooked. Clinicians should be mindful of this condition, and include a primary versus secondary pituitary abscess in the differential workup on such cases.

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