2020
DOI: 10.1007/s10555-020-09863-0
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piRNAs: biogenesis and their potential roles in cancer

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Cited by 98 publications
(66 citation statements)
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References 59 publications
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“…Among them, mTOR plays a key role in tumor tumorigenesis and development. And multiple studies have suggested that tumors typically over-activate the AKT/mTOR signaling pathway [6,7]. Therefore, mTOR inhibitors are widely used in the research of targeted therapy for tumors, organ transplantation, rheumatoid arthritis, and other diseases.…”
Section: Introductionmentioning
confidence: 99%
“…Among them, mTOR plays a key role in tumor tumorigenesis and development. And multiple studies have suggested that tumors typically over-activate the AKT/mTOR signaling pathway [6,7]. Therefore, mTOR inhibitors are widely used in the research of targeted therapy for tumors, organ transplantation, rheumatoid arthritis, and other diseases.…”
Section: Introductionmentioning
confidence: 99%
“…It follows the shape and direction of the ECF, which reduced the outflow of intestinal fistula and improved the success rate of closure treatment (Huang et al, 2017). And 3D printing can also be used to make cardiac valves (Guo, Li, Du, & Zhu, 2020). Some middle‐aged and elderly people have calcification deposits on their heart valves due to aortic occlusion, which obstructs the heart valves from opening or closing completely.…”
Section: D Printing and Personal Implantsmentioning
confidence: 99%
“…Current studies indicated that piRNA and PIWI are signi cantly abnormally expressed in gastric, breast, kidney, colon, and lung cancers, and are involved in the initiation, progression, and metastasis of cancers, which may be the potential diagnostic tools, prognostic markers, and therapeutic targets for cancers. So PNLDC1 might affect the development and progress through regulating piRNA in colon cancer [25] .…”
Section: Disscussionmentioning
confidence: 99%