Pirbuterol Syrup — Treatment of Asthma in Children in a Residential Asthma Clinic

Viallat,; Boutin, C; Razzouk, H

doi:10.1111/j.1742-1241.1984.tb07736.x

Int J Clinical Practice

1984

DOI: 10.1111/j.1742-1241.1984.tb07736.x

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Pirbuterol Syrup — Treatment of Asthma in Children in a Residential Asthma Clinic

Viallat Viallat¹,

C Boutin²,

H Razzouk³

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1985

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Pirbuterol A Preliminary Review of its Pharmacological Properties and Therapeutic Efficacy in Reversible Bronchospastic Disease

Richards¹,

Brogden²

1985

Drugs

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Pirbuterol is a beta-adrenoceptor agonist which differs structurally from salbutamol in the substitution of a pyridine ring for the benzene ring. In common with salbutamol, pirbuterol demonstrates both bronchodilatory and cardiovascular effects. Generally, improvements of up to 25% are noted in forced expiratory volume in 1 second (FEV1) [versus baseline or placebo] in asthmatic patients treated with pirbuterol for several months. In individual 12-week double-blind comparative studies, pirbuterol aerosol appeared similar to orciprenaline (metaproterenol) aerosol, and orally administered pirbuterol appeared similar to orally administered salbutamol in bronchodilator efficacy. However, well-designed long term comparative studies are needed to more clearly define the comparative efficacy of pirbuterol and alternative beta-adrenoceptor agonists.

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Pirbuterol A Preliminary Review of its Pharmacological Properties and Therapeutic Efficacy in Reversible Bronchospastic Disease

Richards¹,

Brogden²

1985

Drugs

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Pirbuterol Syrup — Treatment of Asthma in Children in a Residential Asthma Clinic

Cited by 1 publication

References 7 publications

Pirbuterol A Preliminary Review of its Pharmacological Properties and Therapeutic Efficacy in Reversible Bronchospastic Disease

Pirbuterol A Preliminary Review of its Pharmacological Properties and Therapeutic Efficacy in Reversible Bronchospastic Disease

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