piR-823 tale as emerging cancer-hallmark molecular marker in different cancer types: a step-toward ncRNA-precision
Fatma H. Shaker,
Eman F. Sanad,
Hesham Elghazaly
et al.
Abstract:PIWI-interacting RNAs (piRNAs) have received a lot of attention for their functions in cancer research. This class of short non-coding RNAs (ncRNA) has roles in genomic stability, chromatin remodeling, messenger RNA (mRNA) integrity, and genome structure. We summarized the mechanisms underlying the biogenesis and regulatory molecular functions of piRNAs. Among all piRNAs studied in cancer, this review offers a comprehensive analysis of the emerging roles of piR-823 in various types of cancer, including colorec… Show more
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