2014
DOI: 10.1136/neurintsurg-2014-011355
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Pipeline endovascular device for the treatment of intracranial aneurysms at the level of the circle of Willis and beyond: multicenter experience

Abstract: The pipeline embolization device provides a feasible and technically safe solution for aneurysms at and beyond the circle of Willis. Preliminary results are promising but larger series with longer term follow-up examinations are required to show the long term safety and durability of this treatment alternative.

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Cited by 53 publications
(31 citation statements)
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“…These short-term studies were the only controls for 71.6% of all patients followed up and must surely have contributed to the low occlusion rates. A Spanish–American multicenter study showed that 6 months after treatment of bifurcation aneurysms using FDs, occlusion rates were as low as 64% 10. Yavuz et al 8 emphasized in their series that after 1–3 months a decrease in aneurysm diameter can be expected, whereas complete occlusion begins at about 6 months and might take up to 18 months.…”
Section: Discussionmentioning
confidence: 99%
“…These short-term studies were the only controls for 71.6% of all patients followed up and must surely have contributed to the low occlusion rates. A Spanish–American multicenter study showed that 6 months after treatment of bifurcation aneurysms using FDs, occlusion rates were as low as 64% 10. Yavuz et al 8 emphasized in their series that after 1–3 months a decrease in aneurysm diameter can be expected, whereas complete occlusion begins at about 6 months and might take up to 18 months.…”
Section: Discussionmentioning
confidence: 99%
“…In 2014, Martínez-Galdámez et al14 published a multicenter study of 25 patients of distal aneurysms treated with the Pipeline embolization device. They reported three technical complications with no clinical consequences: one acute branch occlusion resolved after increasing arterial pressure; one slow opacification of the inferior trunk of the MCA which resolved with an intrarterial reopro; and one focal subarachnoid hemorrhage secondary to distal perforation with the microwire during an exchange maneuver.…”
Section: Discussionmentioning
confidence: 99%
“…Martínez-Galdámez et al also looked at the use of PED to treat 25 aneurysms beyond the circle of Willis. 49 Their series had a complete occlusion rate of 64%, and the remaining 36% had significantly reduced residual filling. When evaluating side branches that were covered by PED placement, 79% were found to be patent at follow-up.…”
mentioning
confidence: 99%