Pineal Dysgerminoma: A Misleading Clinical Course With Potential Life-Threatening Consequences

Abstract

Torres et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Neuro-otology symptoms as the early sign in pediatric patient with a pineal gland tumor: a case report

“…Zhang et al proposed 4 hypotheses to explain this regression, including radiation exposure, surgical procedures, effects of steroids, and immunotherapy. No clinical details are available in this patient; however, clinical improvement in our patient occurred after the patient underwent a VP shunt and steroid administration [7] .…”

“…Serum biomarkers and cerebrospinal fluid analysis can complement diagnostic data before invasive procedures are performed. Therefore, research on new diagnostic markers, therapeutic approaches, and follow-up guidelines is very important regarding tumor cases in the pineal region [ 7 , 8 ].…”

“…Awa et al described a study of 93 patients to clarify imaging features for differentiation of pineal germinoma and other pineal region tumors classified as germinoma, non-germinomatous germ cell tumors, pineal parenchymal tumors, and other tumors of the pineal region. Tumor extension in both thalamic and peritumoral edema is specific for differentiating germinoma from non-germinomatous germ cell tumors and pineal parenchymal tumors [ 7 , 11 , 15 ].…”