Pinch purpura: A clinical clue for primary systemic amyloidosis

Pinch purpura; an acute presentation of systemic amyloidosis under general anaesthesia

“…Pinch purpura is a cutaneous manifestation of systemic amyloidosis [1,2]. It typically occurs above the nipple line and is often seen in the webbing of the neck, peri-orbital areas and the eyelids.…”

“…It typically occurs above the nipple line and is often seen in the webbing of the neck, peri-orbital areas and the eyelids. Amyloid deposition in the skin and blood vessel wall causes capillary fragility and leads to intracutaneous micro-and macro-haemorrhages [1,2]. Although the diagnosis of systemic amyloidosis under general anaesthesia is rare, items adhering to the skin (e.g.…”