PIN62 Recognising the broader value of vaccines in HTA: ready for prime time?

Brassel, Simon; Neri, Margherita; Steuten, Lotte Maria Gertruda

doi:10.1016/j.jval.2021.04.1250

Cited by 2 publications

(2 citation statements)

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“…This analysis was inspired by a recent exercise conducted by the British Office of Health Economics (OHE) [ 9 ] and follows the methodological approach of the handbook of immunization economics from Harvard’s DOVE initiative [ 10 ].…”

Section: Introductionmentioning

confidence: 99%

Return on Investment (ROI) of Three Vaccination Programmes in Italy: HPV at 12 Years, Herpes Zoster in Adults, and Influenza in the Elderly

Barbieri

Boccalini

2023

Vaccines

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The calculation of the return on investment (ROI) allows the estimation of the opportunity cost of a series of interventions and can therefore help to make allocative choices. The objective of this study is to estimate the ROI of three vaccinations (HPV for adolescents, HZ for adults, and influenza for the elderly) in the Italian context, considering the impact of increasing vaccination coverage based on target objectives of the National Immunization Plan (PNPV) 2017–2019 and accounting for different eligibility criteria of each vaccination. Three separate static cohort models were constructed, including the eligible population for these vaccinations on the basis of the PNPV 2017–2019 and following this population until death (lifetime horizon) or until vaccination waning. Each model compares the level of investment at current vaccine coverage rates (current VCRs scenario) with that of optimal NIP target VCRs with a non-vaccination scenario. The ROI for HPV vaccination was the highest among the programs compared and was always above 1 (range: 1.4–3.58), while lower values were estimated for influenza vaccination in the elderly (range 0.48–0.53) and for vaccination against HZ (range: 0.09–0.27). Our analysis showed that a significant proportion of savings generated by vaccination programs occurred outside the NHS perspective and might often not be estimated with other forms of economic evaluation.

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Section: Introductionmentioning

confidence: 99%

Return on Investment (ROI) of Three Vaccination Programmes in Italy: HPV at 12 Years, Herpes Zoster in Adults, and Influenza in the Elderly

Barbieri

Boccalini

2023

Vaccines

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“…These inconsistencies are a fundamental issue when considering trade-offs against a broader public sector spending budget. Recently, a number of authors have highlighted the importance of shifting the allocation framework and research towards an 'all-encompassing' multi-sector approach [2,[21][22][23]. This could begin to ameliorate these shortcomings.…”

Section: Introductionmentioning

confidence: 99%

Resource allocation in public sector programmes: does the value of a life differ between governmental departments?

Cubi-Molla,

Mott,

Henderson

et al. 2023

Cost Eff Resour Alloc

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Background The value of a life is regularly monetised by government departments for informing resource allocation. Guidance documents indicate how economic evaluation should be conducted, often specifying precise values for different impacts. However, we find different values of life and health are used in analyses by departments within the same government despite commonality in desired outcomes. This creates potential inconsistencies in considering trade-offs within a broader public sector spending budget. We provide evidence to better inform the political process and to raise important issues in assessing the value of public expenditure across different sectors. Methods Our document analysis identifies thresholds, explicitly or implicitly, as observed in government-related publications in the following public sectors: health, social care, transport, and environment. We include both demand-side and supply-side thresholds, understood as societies’ and governments’ willingness to pay for health gains. We look at key countries that introduced formal economic evaluation processes early on and have impacted other countries’ policy development: Australia, Canada, Japan, New Zealand, the Netherlands, and the United Kingdom. We also present a framework to consider how governments allocate resources across different public services. Results Our analysis supports that identifying and describing the Value of a Life from disparate public sector activities in a manner that facilitates comparison is theoretically meaningful. The optimal allocation of resources across sectors depends on the relative position of benefits across different attributes, weighted by the social value that society puts on them. The value of a Quality-Adjusted Life Year is generally used as a demand-side threshold by Departments of transport and environment. It exceeds those used in health, often by a large enough proportion to be a multiple thereof. Decisions made across departments are generally based on an unspecified rationing rule. Conclusions Comparing government expenditure across different public sector departments, in terms of the value of each department outcome, is not only possible but also desirable. It is essential for an optimal resource allocation to identify the relevant social attributes and to quantify the value of these attributes for each department.

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PIN62 Recognising the broader value of vaccines in HTA: ready for prime time?

Cited by 2 publications

References 0 publications

Return on Investment (ROI) of Three Vaccination Programmes in Italy: HPV at 12 Years, Herpes Zoster in Adults, and Influenza in the Elderly

Return on Investment (ROI) of Three Vaccination Programmes in Italy: HPV at 12 Years, Herpes Zoster in Adults, and Influenza in the Elderly

Resource allocation in public sector programmes: does the value of a life differ between governmental departments?

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