Pin19 a Cost-Effectiveness Analysis of a Prophylactic Cervical Cancervaccine in Germany: Results From a Health Economic Model

Hammerschmidt, Thomas; Siebert, Uwe; Schwarz, TF; Schneider, Antonius; Rogoza, RM; Ferko, Nicole; Welte, R

doi:10.1016/s1098-3015(10)65526-x

Cited by 2 publications

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“…Thus, the vaccine might be considered as a means of achieving increased efficacy and cost-effectiveness in screening programmes in the future [50,51], particularly for younger age groups.…”

Section: Discussionmentioning

confidence: 99%

“…A HPV vaccine is available, and some clinical studies in Italy and Germany showed that use of the vaccine significantly reduces the incidence of cervical cancer. Thus, the vaccine might be considered as a means of achieving increased efficacy and cost-effectiveness in screening programmes in the future [ 50 , 51 ], particularly for younger age groups.…”

Section: Discussionmentioning

confidence: 99%

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Elucidating the spatially varying relation between cervical cancer and socio-economic conditions in England

Cheng

Atkinson

Shahani

2011

International Journal of Health Geographics

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BackgroundGeographically weighted Poisson regression (GWPR) was applied to the relation between cervical cancer disease incidence rates in England and socio-economic deprivation, social status and family structure covariates. Local parameters were estimated which describe the spatial variation in the relations between incidence and socio-economic covariates.ResultsA global (stationary) regression model revealed a significant correlation between cervical cancer incidence rates and social status. However, a local (non-stationary) GWPR model provided a better fit with less spatial correlation (positive autocorrelation) in the residuals. Moreover, the GWPR model was able to represent local variation in the relations between cervical cancer incidence and socio-economic covariates across space, whereas the global model represented only the overall (or average) relation for the whole of England. The global model could lead to misinterpretation of the relations between cervical cancer incidence and socio-economic covariates locally.ConclusionsCervical cancer incidence was shown to have a non-stationary relationship with spatially varying covariates that are available through national datasets. As a result, it was shown that if low social status sectors of the population are to be targeted preferentially, this targeting should be done on a region-by-region basis such as to optimize health outcomes. While such a strategy may be difficult to implement in practice, the research does highlight the inequalities inherent in a uniform intervention approach.

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“…Thus, the vaccine might be considered as a means of achieving increased efficacy and cost-effectiveness in screening programmes in the future [50,51], particularly for younger age groups.…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Elucidating the spatially varying relation between cervical cancer and socio-economic conditions in England

Cheng

Atkinson

Shahani

2011

International Journal of Health Geographics

View full text Add to dashboard Cite

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HPV vaccine worth a shot in Europe

2007

Pharmacoecon. Outcomes News

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On a global scale, cervical cancer ranks as the number two cancer-related death in women. In spite of screening programmes, about 5.5 million new cases of cervical cancer are newly diagnosed each year in the US alone. Human papillomavirus (HPV) has been implicated as a causal factor in cervical cancer, with HPV DNA detected in up to 99.7% of all such cancers. Safe and effective vaccines that prevent HPV infection are now available in Europe, and mandatory immunisation programmes for adolescent females have been discussed, both in Europe and the US. Such programmes have prompted controversy over the ethics and possible unintended negative consequences that may result. In addition, the currently available HPV vaccines are costly, and the costs and outcomes associated with the use of such vaccines were evaluated in several studies presented at the 10th

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Pin19 a Cost-Effectiveness Analysis of a Prophylactic Cervical Cancervaccine in Germany: Results From a Health Economic Model

Cited by 2 publications

References 0 publications

Elucidating the spatially varying relation between cervical cancer and socio-economic conditions in England

Elucidating the spatially varying relation between cervical cancer and socio-economic conditions in England

HPV vaccine worth a shot in Europe

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