Abstract:OBJECTIVES: In Europe, meningococcal serogroup B is the most common cause of invasive meningococcal disease. The disease incidence is the highest among infants, young children and adolescents, while adolescents are considered the key transmitters of meningococci in the population. The disease is rare, but deadly and can cause permanent sequelae. The two new vaccines (4CMenB and rLP2086) were licensed in 2013 and 2017, respectively. Although the cost-effectiveness of vaccination with the vaccine 4CMenB has been… Show more
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