Pimpinella anisum and female disorders: A review

Mahboubi, Mohaddese; Mahboubi, Mona

doi:10.1016/j.phyplu.2021.100063

Cited by 13 publications

(12 citation statements)

References 34 publications

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“…13 Nonetheless, aniseed has a long history of use as a folk remedy during pregnancy, childbirth, and lactation and is considered safe when used at recommended dosages based on historical practices. 3,8,10,87 Summaries of these traditional medicine usages are available from the European Medicines Agency describing dosing and restrictions. [11][12][13] The range of doses recommended in these traditional remedies is broad.…”

Section: Potential Toxicitymentioning

confidence: 99%

“…In ancient times, aniseed was used to aid childbirth and stimulate milk production 8 and continues to be recommended for diverse maladies in folk medicines. Primarily because of the presence of trans -anethole, the fruit and essential oil are used in traditional therapies, for example, for relief of coughs, respiratory congestion, migraines, gastrointestinal (GI) distress, and colic; treatment of skin infections; as tranquilizer and aphrodisiac; and to improve lactation 4,5,9–13 .…”

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confidence: 99%

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Anise

Singletary¹

2022

Nutr Today

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Anise ( Pimpinella anisum L., family Apiaceae) is an aromatic annual herb native to the eastern Mediterranean region and western Asia. Although the small fruit is incorrectly referred to as a seed, nonetheless, the fruit is commonly known as aniseed. When ripe and dried, it is the popular spice. Aniseed and its essential oil are used in traditional therapies, for example, for relief of coughs, respiratory congestion, migraines, gastrointestinal distress, and colic; for treatment of skin infections; as a tranquilizer and aphrodisiac; and to improve lactation. Limited and preliminary clinical research has examined the efficacy of aniseed toward diabetes, dysmenorrhea, and menopausal hot flashes. Antioxidant, anti-inflammatory, and antimicrobial properties also were identified. The present narrative review summarizes human and animal studies reporting potential health benefits of aniseed and highlights areas for future research. Nutr Today 2022;57(2):96-109 A nise ( Pimpinella anisum L., family Apiaceae) is an aromatic annual herb native to the eastern Mediterranean region and western Asia (Figure 1) and cultivated in numerous regions such as southern Europe, northern Africa, South America, China, and Japan. Turkey, Egypt, and Spain are major exporters of this herb, whereas Russia, Spain, and Poland are major suppliers of its oil. The small fruit is incorrectly referred to as a seed. Nonetheless, the fruit is commonly known as aniseed, which when ripe and dried is the popular spice. Aniseed has a sweet, aromatic taste similar to licorice. The fruit and essential oil are used extensively as a flavoring ingredient in numerous foods, including baked goods, sweets, puddings, curries, and frozen dairy desserts, to name a few. The essential oil also is used in perfumes, lotions, soaps, cough preparations, and gum and oral health products. In the food industry, it acts as an antioxidant and preservative. In addition, aniseed is distilled with ethanol to yield distinctive, traditional alcoholic beverages such as anis, Arabian arak, French pastis, Greek ouzo, Russian allasch, Turkish raki, German küstennebel, Italian sambuca, and South American aguardiente. [1][2][3][4] Combining water with these alcoholic beverages in mixed drinks creates a milky cloudiness. This is due to the precipitation of congeners and by-products of distillation that are most soluble in ethanol compared with ethanol and water. In regional foods, this spice is a part of, for example, German springerle or anise-flavored cookies. For these cookies, anise oil (1/ 2 tsp) or extract (1 tsp) can be added directly to the dough, or on the other hand, toasted aniseeds can be distributed on the cookie sheets before baking. Greek butter cookies (koulourakia), traditionally made for Easter and Christmas celebrations, include aniseed (1/2 tsp) and ouzo (1 tbsp) among its flavorings. Likewise, aniseed cookies found in bakeries throughout the Middle East are prepared with ground anise and fennel seeds and savored with a cup of tea or coffee. Preparation of Italian an...

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Section: Potential Toxicitymentioning

confidence: 99%

mentioning

confidence: 99%

Anise

Singletary¹

2022

Nutr Today

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“…In terms of chemical composition, approximately 90–80% of Pimpinella Anisum is Anethole [ 24 ], which is known to lead to increased prolactin stimulation and milk production in animals [ 25 , 26 ]. A recent review of the literature in this field revealed only further studies including animals, and none thus far including human participants [ 27 ]. This provides a unique opportunity to conduct founding research into the effects of Pimpinella Anisum on human milk volume, and subsequent thriving of the premature infant as it is reasonable to assume that such effects seen in animal populations may be similar in humans.…”

Section: Introductionmentioning

confidence: 99%

The effect of Pimpinella Anisum herbal tea on human milk volume and weight gain in the preterm infant: a randomized controlled clinical trial

Khalili

Amiri‐Farahani

Haghani

et al. 2023

BMC Complement Med Ther

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Background and aims Human milk supports pre-term infants to thrive. Yet human milk production can be inhibited when infants are born prematurely. Pimpinella Anisum has been evidenced to increase milk production and infant weight gain in previous animal studies. The present study aimed to determine the effect of Pimpinella Anisum herbal tea on human milk volume and preterm infant weight in human populations for the first time. Methods Human milk supports pre-term infants to thrive. Yet human milk production can be inhibited when infants are born prematurely. Pimpinella Anisum has been evidenced to increase milk production and infant weight gain in previous animal studies. The present study aimed to determine the effect of Pimpinella Anisum herbal tea on human milk volume and preterm infant weight in human populations for the first time. Results There was a statistically significant difference in terms of milk volume in the first, third, fourth, fifth, sixth and seventh days between the three groups of intervention, placebo, and control (p < 0.05). On the first day, the mean volume of pumped milk in the intervention group was significantly higher than the control group (p = 0.008). On the second day, there was no statistically significant difference between groups. On the third, fourth, fifth, sixth and seventh days, the mean volume of pumped milk in the intervention group was significantly higher than the placebo and control groups (p < 0.05). There was no statistically significant difference in terms of preterm infant weight on days 0, 3 and 7 between the three groups. Conclusion The use of Pimpinella Anisum or ‘Anise’ tea can increase the volume of human milk and since no specific side effects have been reported in its use, it may be incorporated easily, cheaply, and effectively in practice where appropriate to the benefit of preterm infant nutrition worldwide.

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“…The in vitro studies proved the antimicrobial and antioxidant activity of essential oil from seeds (Topuz et al ., 2016; Amer & Aly, 2019). In addition, there is evidence for its potential properties for issues of health concern in animals and humans (Alotaibi, 2020; Mahboubi & Mahboubi, 2021). Recent studies evaluated the application of essential oil from aniseed in food production, for example in minced beef preparation (Khanjari et al ., 2019).…”

Section: Introductionmentioning

confidence: 99%

Isolation of antimicrobial compounds from aniseed and techno‐economic feasibility report for industrial‐scale application

Κουτίνας

2022

Int J of Food Sci Tech

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Summary This work evaluates the antimicrobial activity of the fractionated aqueous extract obtained from the aerial parts of aniseed. Fifteen fractions were collected by column chromatography using ethanol and water as mobile phases. All fractions were tested as potential antimicrobial agents against three common food‐spoilage microorganisms: a yeast (Saccharomyces cerevisiae), a mold (Aspergillus awamori) and a bacterium (Lactobacillus delbrueckii subsp. bulgaricus). Fraction 2 exhibited the highest antimicrobial activity in both types of susceptibility test, and therefore, it was further studied for the identification of bioactive compounds. GC‐MS analysis of Fraction 2 revealed the presence of threo‐Anethole glycol. Based on laboratory‐scale experiments, a process flowsheet for potential industrial‐scale application is proposed combined with a techno‐economic feasibility report. Fraction 2 with the detected compound threo‐Anethole glycol showed promising results encouraging the attempts for industrial‐scale application of antimicrobial compounds produced from aniseed.

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Pimpinella anisum and female disorders: A review

Cited by 13 publications

References 34 publications

Anise

Anise

The effect of Pimpinella Anisum herbal tea on human milk volume and weight gain in the preterm infant: a randomized controlled clinical trial

Isolation of antimicrobial compounds from aniseed and techno‐economic feasibility report for industrial‐scale application

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