Pilotprojekt zur Erfassung der inneren Nickelbelastung weiblicher Patientinnen einer dermatologisch-immunologischen Klinik

Nickel and its Compounds [BAT Value Documentation, 2010]

“…The medians or mean values vary from 0.6 to 1.2 μg/l, the 95th percentiles from 1.5 to 3.9 μg/l. The fact that in the study by Schwegler et al (2007) patients of a dermatological clinic, and in this case women only, were examined must be taken into account. The calculated 95th percentile of 3.9 μg/l is higher than in the other six studies in which the values ranged between 1.5 and 2.5 μg/l.…”

“…In 163 female patients of a clinic and polyclinic for dermatology aged 18-46 years, the creatinine-related nickel concentrations are in the range of 0.12-10.43 μg/g creatinine (median 1.22 μg/g creatinine). Per liter urine, the 95th percentiles of nickel excretion in female test persons aged between 18 and 30 years and between 31 and 46 years were 3.77 μg/l and 3.98 μg/l, respectively (Schwegler et al 2007). As analytical method, GF-AAS after chelate formation was used.…”