Piloting and validation of a novel self‐administered online cognitive screening tool in normal older persons: the Cognitive Function Test

Eve, Catharine Trustram; Jager, Celeste A. de

doi:10.1002/gps.3993

Cited by 32 publications

(24 citation statements)

References 49 publications

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“…This is in the high end of previous reports. The CSI memory factor had a .52 correlation to the Buschke Selective Reminding Test (Erlanger et al, 2002 ), CFT episodic memory recognition had a .39 correlation to Total Doors and People, and CFT episodic memory recall had a .43 correlation to People recall (Trustram Eve & de Jager, 2014 ). One study found the CogState One-Back and Learn tasks to correlate .54 and .83 to the Brief Visual Memory Test (Maruff et al, 2009 ).…”

Section: Discussionmentioning

confidence: 99%

“…Generally these batteries require a test administrator—for example, CNS Vital Signs (Gualtieri & Johnson, 2006 ) and Cognitive Stability Index (CSI; Erlanger et al, 2002 ). Still, some batteries are completely self-administered—for example, Cognitive Function Test (CFT; Trustram Eve & de Jager, 2014 ), Computerized Self Test (COGselftest; Dougherty et al, 2010 ), and CogState (Hammers et al, 2012 ; Maruff et al, 2009 ). Although being completely self-administered, several web-based test systems seem to lack features making them optimal for organized large-scale assessment, such as an administrative user interface for designing, deploying, and monitoring assessments.…”

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confidence: 99%

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Initial validation of a web-based self-administered neuropsychological test battery for older adults and seniors

Hansen

Haferstrom

Brunner

et al. 2015

Journal of Clinical and Experimental Neuropsychology

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Introduction: Computerized neuropsychological tests are effective in assessing different cognitive domains, but are often limited by the need of proprietary hardware and technical staff. Web-based tests can be more accessible and flexible. We aimed to investigate validity, effects of computer familiarity, education, and age, and the feasibility of a new web-based self-administered neuropsychological test battery (Memoro) in older adults and seniors. Method: A total of 62 (37 female) participants (mean age 60.7 years) completed the Memoro web-based neuropsychological test battery and a traditional battery composed of similar tests intended to measure the same cognitive constructs. Participants were assessed on computer familiarity and how they experienced the two batteries. To properly test the factor structure of Memoro, an additional factor analysis in 218 individuals from the HUNT population was performed. Results: Comparing Memoro to traditional tests, we observed good concurrent validity (r = .49–.63). The performance on the traditional and Memoro test battery was consistent, but differences in raw scores were observed with higher scores on verbal memory and lower in spatial memory in Memoro. Factor analysis indicated two factors: verbal and spatial memory. There were no correlations between test performance and computer familiarity after adjustment for age or age and education. Subjects reported that they preferred web-based testing as it allowed them to set their own pace, and they did not feel scrutinized by an administrator. Conclusions: Memoro showed good concurrent validity compared to neuropsychological tests measuring similar cognitive constructs. Based on the current results, Memoro appears to be a tool that can be used to assess cognitive function in older and senior adults. Further work is necessary to ascertain its validity and reliability.

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Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

Initial validation of a web-based self-administered neuropsychological test battery for older adults and seniors

Hansen

Haferstrom

Brunner

et al. 2015

Journal of Clinical and Experimental Neuropsychology

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“…As suggested by others [31], the mean value plus 1 SD was used as cutoff for one group with good DS performance and another group with poor DS performance. The mean values of the DS and the wBCST for both groups were calculated and the significance of the differences was calculated using a non-parametric Mann-Whitney U-test.…”

Section: Methodsmentioning

confidence: 99%

Can a Novel Web-Based Computer Test Predict Poor Simulated Driving Performance? A Pilot Study With Healthy and Cognitive-Impaired Participants

Nef

Müri²,

Bieri³

et al. 2013

J Med Internet Res

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BackgroundDriving a car is a complex instrumental activity of daily living and driving performance is very sensitive to cognitive impairment. The assessment of driving-relevant cognition in older drivers is challenging and requires reliable and valid tests with good sensitivity and specificity to predict safe driving. Driving simulators can be used to test fitness to drive. Several studies have found strong correlation between driving simulator performance and on-the-road driving. However, access to driving simulators is restricted to specialists and simulators are too expensive, large, and complex to allow easy access to older drivers or physicians advising them. An easily accessible, Web-based, cognitive screening test could offer a solution to this problem. The World Wide Web allows easy dissemination of the test software and implementation of the scoring algorithm on a central server, allowing generation of a dynamically growing database with normative values and ensures that all users have access to the same up-to-date normative values.ObjectiveIn this pilot study, we present the novel Web-based Bern Cognitive Screening Test (wBCST) and investigate whether it can predict poor simulated driving performance in healthy and cognitive-impaired participants.MethodsThe wBCST performance and simulated driving performance have been analyzed in 26 healthy younger and 44 healthy older participants as well as in 10 older participants with cognitive impairment. Correlations between the two tests were calculated. Also, simulated driving performance was used to group the participants into good performers (n=70) and poor performers (n=10). A receiver-operating characteristic analysis was calculated to determine sensitivity and specificity of the wBCST in predicting simulated driving performance.ResultsThe mean wBCST score of the participants with poor simulated driving performance was reduced by 52%, compared to participants with good simulated driving performance (P<.001). The area under the receiver-operating characteristic curve was 0.80 with a 95% confidence interval 0.68-0.92.ConclusionsWhen selecting a 75% test score as the cutoff, the novel test has 83% sensitivity, 70% specificity, and 81% efficiency, which are good values for a screening test. Overall, in this pilot study, the novel Web-based computer test appears to be a promising tool for supporting clinicians in fitness-to-drive assessments of older drivers. The Web-based distribution and scoring on a central computer will facilitate further evaluation of the novel test setup. We expect that in the near future, Web-based computer tests will become a valid and reliable tool for clinicians, for example, when assessing fitness to drive in older drivers.

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“…AlzU.org has been shown to significantly improve medical knowledge about AD prevention and improve willingness to participate in an AD prevention clinical trial (15). AlzU.org also contains a number of activities, including the option to take online cognitive tests which may be particularly useful for detecting and longitudinally assessing prodromal pathological changes due to AD (i.e., Cognitive Function Test (16) and Neurotrack (17)) in an easily accessible online format. Currently, AlzU.org provides 6 evidence-based interactive lessons (~10 minutes each) and 12 activities (e.g.…”

Section: Applying the Conceptual Frameworkmentioning

confidence: 99%

The Alzheimer’s Prevention Clinic at Weill Cornell Medical College / New York - Presbyterian Hospital: Risk Stratification and Personalized Early Intervention

Seifan¹,

Isaacson²

2015

J Prev Alz Dis

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In July 2013, Weill Cornell Medical College founded the first Alzheimer’s Prevention Clinic (APC) in the United States, providing direct clinical care to family members of patients with Alzheimer’s disease (AD) as part of the Weill Cornell Memory Disorders Program. At the APC, patients seeking to lower their AD risk undergo a comprehensive assessment, receive a personalized plan based on rapidly evolving scientific evidence, and are followed over time using validated as well as emerging clinical and research technologies. The APC approach applies the principles of pharmacogenomics, nutrigenomics and clinical precision medicine, to tailor individualized therapies for patients. Longitudinal measures currently assessed in the clinic include anthropometrics, cognition, blood biomarkers (i.e., lipid, inflammatory, metabolic, nutritional) and genetics, as well as validated, self-reported measures that enable patients to track several aspects of health-related quality of life. Patients are educated on the fundamental concepts of AD prevention via an interactive online course hosted on Alzheimer’s Universe (www.AlzU.org), which also contains several activities including validated computer-based cognitive testing. The primary goal of the APC is to employ preventative measures that lower modifiable AD risk, possibly leading to a delay in onset of future symptoms. Our secondary goal is to establish a cohort of at-risk individuals who will be primed to participate in future AD prevention trials as disease-modifying agents emerge for testing at earlier stages of the AD process. The clinical services are intended to lower concern for future disease by giving patients a greater sense of control over their brain health.

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Piloting and validation of a novel self‐administered online cognitive screening tool in normal older persons: the Cognitive Function Test

Abstract: The online CFT was shown to be suitable for self-administration in online format (with a mouse response mode) for this midlife age group. Individuals may wish to monitor their cognitive performance before memory concerns are sufficient to warrant visiting a GP or memory clinic.

Cited by 32 publications

References 49 publications

Initial validation of a web-based self-administered neuropsychological test battery for older adults and seniors

Initial validation of a web-based self-administered neuropsychological test battery for older adults and seniors

Can a Novel Web-Based Computer Test Predict Poor Simulated Driving Performance? A Pilot Study With Healthy and Cognitive-Impaired Participants

The Alzheimer’s Prevention Clinic at Weill Cornell Medical College / New York - Presbyterian Hospital: Risk Stratification and Personalized Early Intervention

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