Pilot study to investigate the efficacy of a 1 per cent selenium sulphide shampoo in the treatment of equine chorioptic mange

Curtis, Cathy

doi:10.1136/vr.144.24.674

Cited by 16 publications

(20 citation statements)

References 4 publications

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“…Treatment of all infested animals must be included in any treatment protocol. Treatments described for horses infested by C. bovis include oral macrocyclic lactones, such as ivermectin, doramectin, eprinomectin and moxidectin, 1,3,12 a local spray application of fipronil, 1,20 local applications of pyrethroids, phosphoric acid, carbamates or combinations thereof, 10,11 and finally, washings with 2% lime sulphur 21 . Topical treatments are complicated by the dense feathering of the horses’ limbs that prevent optimal contact with the medication.…”

Section: Discussionmentioning

confidence: 99%

Combined moxidectin and environmental therapy do not eliminate Chorioptes bovis infestation in heavily feathered horses

Rüfenacht¹,

Roosje²,

Sager³

et al. 2011

Veterinary Dermatology

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Chorioptes bovis infestation is a common cause of pastern dermatitis in the horse, with a predilection in draft horses and other horses with thick hair 'feathers' on the distal limbs. The treatment of this superficial mite is challenging; treatment failure and relapse are common. Furthermore, C. bovis infestation may affect the progression of chronic pastern dermatitis (also known as chronic proliferative pastern dermatitis, chronic progressive lymphoedema and dermatitis verrucosa) in draft horses, manifesting with oedema, lichenification and excessive skin folds that can progress to verruciform lesions. An effective cure for C. bovis infestation would therefore be of great clinical value. In a prospective, double-blind, placebo-controlled study, the efficacy of oral moxidectin (0.4 mg/kg body weight) given twice with a 3 week interval in combination with environmental treatment with 4-chloro-3-methylphenol and propoxur was tested in 19 heavily feathered horses with clinical pastern dermatitis and C. bovis infestation. Follow-up examinations over a period of 180 days revealed significantly more skin crusting in the placebo group than in the treatment group. However, no other differences in clinical signs or the numbers of mites detected were found between the two groups. The results of this study suggest that moxidectin in combination with environmental insecticide treatment as used in this study is ineffective in the treatment of C. bovis in feathered horses.

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Section: Discussionmentioning

confidence: 99%

Combined moxidectin and environmental therapy do not eliminate Chorioptes bovis infestation in heavily feathered horses

Rüfenacht¹,

Roosje²,

Sager³

et al. 2011

Veterinary Dermatology

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“…Topical therapy has been described using selenium sulphide 1 , fipronil 2,3 , ivermectin solution 13 and flumethrin 14 . Reports about use of the latter two drugs are anecdotal only.…”

Section: Discussionmentioning

confidence: 99%

“…Clinical studies have been undertaken to substantiate claims of efficacy for selenium sulphide and fipronil. In a pilot study reported by Curtis 1 1% solution of selenium sulphide was used to shampoo seven horses on days 0, 5 and 10. All horses improved and after three washes were parasite free.…”

Section: Discussionmentioning

confidence: 99%

“…Several studies have been published which evaluate the efficacy of a variety of topical and systemic drugs. Topical drugs that have been investigated include selenium sulphide (Seleen, Ceva) 1 , fipronil (Frontline, Merial) 2–4 and ivermectin (Panomec, Merial) 4 . Systemically administered medications include oral ivermectin (Eqvalan, Merial) 4,5 , and injectable doramectin (Dectomax; Pfizer) 3 .…”

Section: Introductionmentioning

confidence: 99%

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An open study to evaluate topical treatment of equine chorioptic mange with shampooing and lime sulphur solution

Paterson

Coumbe

2009

Veterinary Dermatology

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Chorioptic mange caused by Chorioptes bovis is a common pruritic skin condition of the horse. This surface-browsing parasite usually affects the lower legs (leg mange) but can present as a generalized skin disease. Numerous anecdotal reports exist in the literature about the benefit of lime sulphur as a treatment for surface ectoparasites in the horse. This report studies the use of lime sulphur when applied as a 5% solution, some with and some without prior shampooing and clipping, to treat confirmed cases of chorioptic mange in 22 horses. Horses included in the trial had clinical signs indicative of chorioptic mange and positive identification of chorioptic mites on skin scrapings and tape preparations. Each horse was treated with sulphurated lime dip solution four times at 7-day intervals. Most horses were clipped and/or shampooed prior to treatment. Animals were assigned a score based on a scale of 1-10 to assess the severity of their lesions and degree of behavioural signs. The horses were again scored and examined for mites after four treatments. All animals showed a reduction in scores at the end of the trial and mites were not demonstrated from any animal.

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“…Oral ivermectin paste has been shown to be effective in reducing mite numbers in horses with chorioptic mange, but the dosage protocols tested failed to secure complete elimination of parasites in all treated horses (Littlewood et al 1995). A pilot study using 1% selenium sulphide shampoo for 7 horses with chorioptic mange demonstrated that the treatment was effective in achieving resolution of clinical signs and rendering animals skin-scrape negative for mites (Curtis 1998).…”

Section: Introductionmentioning

confidence: 99%

Chorioptic mange: successful treatment of a case with fipronil

Littlewood

2000

Equine Veterinary Education

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Pilot study to investigate the efficacy of a 1 per cent selenium sulphide shampoo in the treatment of equine chorioptic mange

Cited by 16 publications

References 4 publications

Combined moxidectin and environmental therapy do not eliminate Chorioptes bovis infestation in heavily feathered horses

Combined moxidectin and environmental therapy do not eliminate Chorioptes bovis infestation in heavily feathered horses

An open study to evaluate topical treatment of equine chorioptic mange with shampooing and lime sulphur solution

Chorioptic mange: successful treatment of a case with fipronil

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