Pilot Study of the Total and Phosphorylated Tau Proteins in Early-Stage Multiple Sclerosis
Ieva Masiulienė,
Katryna Pampuščenko,
Gintarė Žemgulytė
et al.
Abstract:Background and Objectives: Recent findings suggest that neurodegeneration starts early in the course of multiple sclerosis (MS) and significantly contributes to the progression of patients’ disability. Tau is a microtubule-binding protein that is known to play a role in the pathophysiology of many neurodegenerative disorders. Newly emerging data on tau protein-induced neurodegenerative processes and its possible involvement in MS suggest that it may be involved in the pathology of early-stage MS. Therefore, th… Show more
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