Pilot Investigation of Changes in Readiness and Confidence to Quit Smoking After E-Cigarette Experimentation and 1 Week of Use

Wagener, Theodore L.; Meier, Ellen; Hale, Jessica; Oliver, Elisha; Warner, Maggie L.; Driskill, Leslie M.; Gillaspy, Stephen R.; Siegel, Michael; Foster, Steven B.

doi:10.1093/ntr/ntt138

Cited by 55 publications

(45 citation statements)

References 21 publications

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“…In the first study (N=20), e-cigarette experimentation was associated with reduced cigarette smoking after one week. 92 Similarly, in a second study involving smokers who were provided e-cigarettes for 24 weeks ( N =40), about 23% reported 30-day cigarette abstinence and about a third reduced cigarette consumption by at least 50%. 93 Results remained similar 18 months later, not including 17 who were lost to follow-up.…”

Section: Discussionmentioning

confidence: 99%

Electronic Nicotine Delivery Systems (“E‐cigarettes”): Review of Safety and Smoking Cessation Efficacy

Harrell

Simmons

Correa

et al. 2014

Otolaryngol.--head neck surg.

119

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Background and Objectives Cigarette smoking is common among cancer patients and is associated with negative outcomes. Electronic nicotine delivery systems (“e-cigarettes”) are rapidly growing in popularity and use, but there is limited information on their safety or effectiveness in helping individuals quit smoking. Data Sources The authors searched PubMed, Web of Science, and additional sources for published empirical data on safety and use of electronic cigarettes as an aid to quit smoking. Review Methods We conducted a structured search of the current literature up to and including November 2013. Results E-cigarettes currently vary widely in their contents and are sometimes inconsistent with labeling. Compared to tobacco cigarettes, available evidence suggests that e-cigarettes are often substantially lower in toxic content, cytotoxicity, associated adverse effects, and secondhand toxicity exposure. Data on the use of e-cigarettes for quitting smoking is suggestive, but ultimately inconclusive. Conclusions Clinicians are advised to be aware that the use of e-cigarettes, especially among cigarette smokers, is growing rapidly. These devices are unregulated, of unknown safety, and of uncertain benefit in quitting smoking. Implications for Practice In the absence of further data or regulation, oncologists are advised to discuss the known and unknown safety and efficacy information on e-cigarettes with interested patients, and to encourage patients to first try FDA-approved pharmacotherapies for smoking cessation.

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Section: Discussionmentioning

confidence: 99%

Electronic Nicotine Delivery Systems (“E‐cigarettes”): Review of Safety and Smoking Cessation Efficacy

Harrell

Simmons

Correa

et al. 2014

Otolaryngol.--head neck surg.

119

View full text Add to dashboard Cite

show abstract

“…[11][12][13][14] However, although there is evidence that e-cigarettes may help some people reduce or even quit smoking, available prospective studies suggest that e-cigarettes are similar to NRT in that most users do not quit smoking. [15][16][17][18][19][20][21] Despite these concerns, a recent cross-sectional, retrospective study found that e-cigarette users in the general population were more likely than NRT users to have quit cigarette smoking. 22 In comparison to cigarettes, available evidence suggests that e-cigarettes are a safer nicotine delivery system.…”

mentioning

confidence: 99%

Expectancies for Cigarettes, E-Cigarettes, and Nicotine Replacement Therapies Among E-Cigarette Users (aka Vapers)

Harrell

Marquinez

Correa

et al. 2014

Nicotine &Amp; Tobacco Research

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“…Similarly, in a small lab study in which smokers were provided an active EC to sample for a week, smokers reduced their CPD by 44% during a 1-week sampling period of ad libitum use. 25 Additionally, smokers reported an increase in readiness and confidence to quit smoking. Unlike the current study, Wagener and colleagues 25 allowed participants to sample three different ECs in the lab (ie, SmokeTip, ProSmoke, and BluCig), selecting one as their preferred product to use over a subsequent sampling week.…”

Section: Discussionmentioning

confidence: 99%

“…In a previous lab-based study, most smokers used three cartridges of this same device per week, with a maximum of seven; therefore seven cartridges were dispensed to provide a sufficient supply for the sampling weeks. 25 Participants and research staff conducting sessions were blinded to dose. All cartridges were pre-loaded by the manufacturer.…”

Section: Productsmentioning

confidence: 99%

A Pilot Randomized Crossover Trial of Electronic Cigarette Sampling Among Smokers

Meier

Wahlquist

Heckman

et al. 2016

NICTOB

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Introduction: Electronic cigarette (EC) use is proliferating, but initial uptake patterns and their influence on smoking remains unclear. This study of EC sampling examines naturalistic uptake of ECs, as well as effects on smoking and perceived reward from smoking and vaping. Methods: Within a double-blind randomized crossover design, smokers (n = 24; 75% male; M age = 48.5 years) smoked as usual for 1 week, followed by two counterbalanced naturalistic (ie, ad libitum use) weeks of either placebo or active first generation ECs. Vaping and regular smoking was measured daily using diaries and at weekly clinic visits. Perceived reward from ECs and intentions/confidence to quit were also assessed. Analyses compared variables during the naturalistic smoking week and each EC week while controlling for sequence and baseline measurements of respective variables. Results: No significant differences emerged between active and placebo EC weeks in vaping or regular smoking, EC reinforcement, and intention/confidence to quit smoking. Satisfaction from smoking (p = .04) and smoking's ability to reduce cravings (p = .003) decreased from the naturalistic to active EC week. Behavioral dependence to cigarettes decreased from the naturalistic (M = 16.5, p = .02) to active (M = 14.7) and placebo (M = 14.2) EC weeks. Conclusions: Few differences emerged in vaping, regular cigarette use, and overall reactions to ECs between active and placebo ECs. Active ECs appeared to decrease reinforcement from smoking, and both active and placebo ECs reduced behavioral dependence to cigarettes. Nicotine (per labeling) may have minimal influence on the uptake of first generation ECs among smokers. Implications: First generation ECs provide an important behavioral/sensorimotor replacement for cigarettes, regardless of nicotine delivery, but substantial substitution may be minimal when smokers are only asked to use ad libitum. However, newer models of EC devices that provide better nicotine delivery should be examined for potential differential patterns of smoking and vaping (eg, decreased smoking and increased vaping) given their suggested greater ability to provide nicotine and behavior/sensorimotor replacement.

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Pilot Investigation of Changes in Readiness and Confidence to Quit Smoking After E-Cigarette Experimentation and 1 Week of Use

Abstract: Among a small convenience sample of unmotivated cigarette smokers, EC experimentation and 1 week of ad libitum use increased readiness and confidence to quit regular cigarettes and reduced regular cigarette smoking.

Cited by 55 publications

References 21 publications

Electronic Nicotine Delivery Systems (“E‐cigarettes”): Review of Safety and Smoking Cessation Efficacy

Electronic Nicotine Delivery Systems (“E‐cigarettes”): Review of Safety and Smoking Cessation Efficacy

Expectancies for Cigarettes, E-Cigarettes, and Nicotine Replacement Therapies Among E-Cigarette Users (aka Vapers)

A Pilot Randomized Crossover Trial of Electronic Cigarette Sampling Among Smokers

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