Pilomatrixoma: a diagnostic pitfall in fine-needle aspiration biopsies. A review from a small county hospital

Lemos, Luciano B.; Brauchle, Randall W.

doi:10.1016/j.anndiagpath.2004.03.004

Cited by 34 publications

(31 citation statements)

References 25 publications

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“…18 Pilomatrixoma can be clinically misdiagnosed as malignant tumors of the salivary gland and cytologically mimic tumors such as mucoepidermoid carcinoma or squamous cell carcinoma. 32 Skin tumors such as dermal eccrine cylindroma or spiradenoma, basal-cell carcinoma of the skin and basaloid squamous carcinoma of the head and neck can produce hyaline globule-like material and are a potential diagnostic pitfall with salivary neoplasms. 28,33 Basal cell adenocarcinoma of the parotid shows almost the same cytologic features of metastatic basal cell carcinoma of the skin in the parotid.…”

Section: Discussionmentioning

confidence: 99%

Diagnostic Difficulties in the Interpretation of Fine Needle Aspirate Samples in Salivary Lesions

Daneshbod¹,

Daneshbod²,

Khademi³

2009

Acta Cytologica

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Section: Discussionmentioning

confidence: 99%

Diagnostic Difficulties in the Interpretation of Fine Needle Aspirate Samples in Salivary Lesions

Daneshbod¹,

Daneshbod²,

Khademi³

2009

Acta Cytologica

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“…Pilomatricoma is cytologically characterized by basaloid cells, ghost (shadow) cells, foreign body giant cells, nucleated squamous cells and calcium deposits on a background of amorphous debris. 1,3,4 Among these, ghost cells are considered the key component, 6,7 and a diagnosis of pilomatricoma should be suspected if the key component is present in combination with the other findings. 6 Early lesions are predominantly composed of basaloid cells, leading to a basaloid cell-rich aspirate.…”

Section: Discussionmentioning

confidence: 99%

Pilomatricoma Mimicking Small Round Cell Tumor on Fine Needle Aspiration Cytology

Thapliyal¹,

Joshi²,

Vaibhav³

et al. 2008

Acta Cytologica

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“…Tek nodül şeklinde daha sık görülür iken multipl pilomatriksoma da rapor edilmiştir 3,4,5 . Gerçek insidansı bilinmemekle birlikte %0,03-%0,1 arasında rapor edilen çalışmalar mevcuttur 6 . Özellikle 20 yaş öncesinde kadınlarda erkeklere göre 3:2 oranında daha sık görülmektedir 1 .…”

Section: Introductionunclassified

Çocuklarda Pilomatriksoma (Kalsifiye Epitelyoma)

Varlıklı¹,

Yıldız²,

Çetin³

et al. 2013

Turkderm

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ÖzetAmaç: Pilomatriksoma veya Malherbe'nin kalsifiye epitelioması kılın pluripotent prekürsör matriks hücrelerinden köken alan, nadir görülen, iyi huylu, sınırlı, kalsifiye epitelyal bir tümördür. Genellikle baş boyun ve üst ekstremitelerde, deri veya deri altında, semptom vermeyen nodül olarak görülür. Bu klinik çalışmada, 20 olgudaki tecrübelerimiz ışığında tümörün epidemiyolojisinin, klinik ve histopatolojik bulgularının, ayırıcı tanısının ve tedavi sonuçlarının tartışılması hedeflenmiştir. Gereç ve Yöntem: Bu çalışmada, 2005-2012 yılları arasında çocuk cerrahisi kliniklerinde deri altı kitlelere eksizyonel biyopsi uygulanan ve patolojik olarak pilomatriksoma tanısı alan 20 olgu retrospektif olarak incelendi. Bulgular: Toplamda 20 olgumuzun 12'si kız (%60), 8'i erkekti (%40). Tanı aldıklarında hastaların ortalama yaşı 9,6 yıldı. Olgularımızın 18 tanesi (%90) tek nodül şeklinde, 2 tanesi (%10) ayrı lokalizasyonlarda çift nodül şeklindeydi. Tümör lokalizasyonları itibari ile %54,5'ü baş-boyun, %31,8'i ekstremite ve %13,6'sı gövdede bulunuyordu. Sonuç: Pilomatriksoma, sık olmamasına rağmen daha çok çocuklarda ve adelosanlarda görülen cerrahi eksizyon ile tedavi edilebilen benin bir deri tümörüdür. Bu olguların tekrarlama ve hatta metastaz riski taşıyan malin formunun atlanmaması için histopatolojik ve klinik özelliklerinin dikkatle değerlendirilmesi gereklidir (Türk derm 2013; 47: 84-7). Anah tar Ke li me ler: Pilomatriksoma, çocuklar Sum maryBackground and Design: Pilomatrixoma calcifying epithelioma of Malherbe is a rare, benign, limited, calcifying epithelial neoplasm that arises from the hair pluripotent precursor matrix cells. It is usually seen in the head and neck and the upper extremities, in the dermis or subcutaneous tissues as an asymptomatic nodule. In this study, we discuss the epidemiology of the tumor, clinical and histopathological findings, differential diagnosis and treatment outcome of pilomatrixoma in the light of our experiences with 20 cases. Materials and Methods: We retrospectively evaluated a total of 20 cases diagnosed with pilomatrixoma with a pathology evaluation after excisional biopsy of the subcutaneous mass at pediatric surgery clinics between 2005 and 2012. Results: Our 20 patients consisted of 12 females (60%) and 8 males (40%). The mean age at the time of diagnosis was 9.6 years. There was a single nodule in 18 cases (90%) and two nodules in separate places in 2 cases (10%). The tumor localization was in the head and neck in 54.5%, the extremities in 31.8%, and the trunk in 13.6%. Conclusion: Pilomatrixomas are rare but usually seen in children and adolescents and this benign skin tumor can be treated with surgical excision. Histopathological and clinical features should be evaluated carefully to prevent missing the malignant form that carries a risk of recurrence and even metastasis. (Turkderm 2013; 47: 84-7)

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Pilomatrixoma: a diagnostic pitfall in fine-needle aspiration biopsies. A review from a small county hospital

Cited by 34 publications

References 25 publications

Diagnostic Difficulties in the Interpretation of Fine Needle Aspirate Samples in Salivary Lesions

Diagnostic Difficulties in the Interpretation of Fine Needle Aspirate Samples in Salivary Lesions

Pilomatricoma Mimicking Small Round Cell Tumor on Fine Needle Aspiration Cytology

Çocuklarda Pilomatriksoma (Kalsifiye Epitelyoma)

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