Pilar Sheath Acanthoma

Neoplasms derived from follicular tissue are extremely rare. Clinically, they are reported as non-symptomatic, slow-growing nodules. These lesions are mainly benign, but the malignant type can occur. Mainly middle-aged people (50–60 years of age) are affected. These carcinomas are mainly localized on the head and neck or torso. They can be locally aggressive and infiltrate surrounding tissue and metastasize to regional lymph nodes. In the minority of cases, distant metastases are diagnosed. Quick and relevant diagnosis is the basis of a treatment for all types of tumors. The patient’s life expectancy depends on multiple prognostic factors, including the primary tumor size and its mitotic count. Patients should be referred to a specialized skin cancer center to receive optimal multidisciplinary treatment. This article tries to summarize all the information that is currently available about pathogenesis, diagnosis, and treatment methods of follicular tumors.

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“…Pilar sheath acanthoma is a benign follicular neoplasm [ 90 ]. Some authors suggest that this tumor is a benign follicular hamartoma.…”

Section: Tumors With Follicular Differentiationmentioning

confidence: 99%

Current Diagnosis and Treatment Options for Cutaneous Adnexal Neoplasms with Follicular Differentiation

Płachta

Kleibert

Czarnecka

et al. 2021

IJMS

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“…Pilar sheath acanthomas are clinically distinctive tumors presenting as a single papule with a central pore, occurring with overwhelming frequency on the upper lip of an adult …”

Section: Tumors Of Isthmic and Infundibular Epitheliummentioning

confidence: 99%

“…Pilar sheath acanthomas are clinically distinctive tumors presenting as a single papule with a central pore, occurring with overwhelming frequency on the upper lip of an adult. 59 Histological features include a central cystic cavity from which radiate acanthotic lobules composed of isthmic ORStype cells, though lesions with a more infundibular appearance may occur (Fig. 11).…”

Section: Pilar Sheath Acanthomamentioning

confidence: 99%

Folliculosebaceous neoplasms: A review of clinical and histological features

Bhawan

2017

The Journal of Dermatology

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Numerous benign and occasionally malignant tumors arise from the folliculosebaceous apparatus. Confusing terminology, rarity of malignant variants and overlapping histological features can lead to diagnostic uncertainty. This review highlights the clinical and histopathological features that help to classify these entities, as well as the various syndromes associated with certain members of this large family of tumors.

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“…Histologically, in the center of the lesion is a cystic dilated hair follicle open to the surface and containing keratinous material (13). Massive proliferation of the outer root sheath epithelium occurs extending from the wall of the dilated follicle into the surrounding areas in all directions.…”

Section: Pilar Sheath Acanthomamentioning

confidence: 99%