Pih11 Quality-of-Life Weights for the U.S. Population: Self-Reported Health Status and Priority Health Conditions, by Demographic Characteristics

Nyman, John A.; Barleen, NA; Be, Dowd; Russell, D.; Coons, SJ; Sullivan, Patrick W.

doi:10.1016/s1098-3015(10)69020-1

Cited by 16 publications

(25 citation statements)

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“…Note that Nyman et al's (2007) education categories were collapsed in order to map them into three categories available in the March CPS and the NLMS. Specifically, GED, high school degree, and "other degree" categories are collapsed into "high school or some college," and bachelor's degree and graduate degree are collapsed into "at least a bachelor's degree."…”

Section: The Value Of Longer Life (Improved Mortality)mentioning

confidence: 99%

“…Estimates of the value of foregone benefits arising from the poorer health status among disadvantaged populations are again based on estimates of health-related quality of life for various education groups reported in Nyman et al (2007), as described above. On average, health-related quality of life for individuals with at least a bachelor's degree differs from that of individuals with less than a high school education by 0.062 points on the 0 to 1 scale; the gap between individuals with at least a bachelor's degree and individuals with a high school education or some college (but not a bachelor's degree) is 0.032.…”

Section: The Value Of Improved Health Statusmentioning

confidence: 99%

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The Economic Value of Improving the Health of Disadvantaged Americans

Schoeni

Dow

Miller

et al. 2011

American Journal of Preventive Medicine

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Section: The Value Of Longer Life (Improved Mortality)mentioning

confidence: 99%

Section: The Value Of Improved Health Statusmentioning

confidence: 99%

The Economic Value of Improving the Health of Disadvantaged Americans

Schoeni

Dow

Miller

et al. 2011

American Journal of Preventive Medicine

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“…We calculated quality-adjusted life expectancies based on estimates of mean life expectancy, declines in quality-of-life weights with age, and preference weights dependent on neurologic outcome (22). Our hypothetical patient had an age of 50 years, based on published literature (17) and institutional experience, with a mean life expectancy of 31.0 additional years (23).…”

Section: Methodsmentioning

confidence: 99%

Cost-Effectiveness Study of Criteria for Screening Cerebrospinal Fluid To Determine the Need for Herpes Simplex Virus PCR Testing

et al. 2017

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The absence of markers of inflammation in the cerebrospinal fluid (CSF) commonly predicts the absence of herpes simplex virus (HSV) central nervous system (CNS) infection. Consequently, multiple authors have proposed and validated criteria for deferring HSV PCR testing of CSF in immunocompetent hosts with normal CSF white blood cell and protein levels (Յ5 cells/mm 3 and Յ50 mg/dl, respectively). Hosts are considered immunocompetent if they are Ն2 years old and have not had HIV or an organ transplant. Adoption of the criteria may erroneously exclude HSV-infected persons from a necessary diagnostic test or, alternatively, reduce the costs associated with HSV tests with minimal to no effect on patient care. Little is known about the cost-effectiveness of this approach. A decision analysis model was developed to evaluate the adoption of criteria for screening HSV tests of CSF. Estimates of input parameter values combined available literature with a multiyear multisite review at two of the largest health care systems in the United States. Adoption of criteria to screen for HSV test need proved cost-effective when less than 1 in 200 patients deferred from testing truly had an HSV CNS infection. Similar to prior studies, none of the deferred cases had HSV encephalitis (n ϭ 3120). Adoption of these criteria in the United States would save an estimated $127 million ($95 million to $158 million [Ϯ25%]) annually. The model calculations remained robust to variation in test cost, prevalence of HSV infection, and random variation to study assumptions. The adoption of criteria to screen HSV PCR tests in CSF represents a cost-effective approach.KEYWORDS cost-effectiveness, herpes simplex virus, polymerase chain reaction M ultiple studies have identified herpes simplex virus (HSV) as the most common cause of encephalitis (1-3). Unlike treatment of other causes of viral encephalitis, treatment of herpes simplex virus with acyclovir (ACV) has the highest recommendation for treatment from the Infectious Diseases Society of America (4). The combination of relatively benign treatment and a poor prognosis without treatment justifies a laboratory workup for many more patients than have the disease. The gold standard test for herpes simplex has become nucleic acid amplification, such as HSV PCR. An alternative approach to PCR proposes to test only select patients who meet specific clinical and laboratory criteria.Over the past 15 years, evidence for excluding herpes simplex virus without HSV PCR has accumulated (5-10). The authors of these studies cited five primary factors as their motivation. First, the spectrum of disease detected by PCR has become less severe and less treatable (e.g., Mollaret's meningitis, HSV-2 meningitis) (11). Second, PCR for HSV has a very low positive rate, between 1% and 3%. Most of the positive results are not

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“…Data sources. Effectiveness of treatment, cost data, and transition probabilities were retrieved from published literature and primary data collection and summarized in Table 1 with their data sources (17,(22)(23)(24)(25)(26)(27)(28)(29)(30)(31)(32)(33)(34).…”

Section: Methodsmentioning

confidence: 99%

“…Life expectancy was adjusted for quality-of-life with mean health-related quality-of-life weights on the basis of published data (Table 1) (32). Effectiveness of treatment.…”

Section: Methodsmentioning

confidence: 99%