Pigmented Villonodular Synovitis of the Thoracic Vertebra Presenting with Progressive Spastic Paraparesis

Abstract

Pigmented villonodular synovitis (PVNS) is a proliferative benign lesion originating from the synovium and commonly affects large joints of the extremities. PVNS can arise from any synovium in the whole body and rarely affects the zygapophyseal joints of the spine. Spinal PVNS is diagnosed mostly after resection of the mass. In our case we present a 22-year-old male patient showing progressive spastic paraparesis with insidious onset of back pain and difficulty of walking in a relatively short period of 1 month. After gross excision of the mass, diagnosis was established through histopathology. Two years of follow-up period reveals complete resolution of the patient's complaints and no recurrence on radiologic images.

Novel ATL1 mutation in a Chinese family with hereditary spastic paraplegia: A case report and review of literature

“…The impairments of the upper motor system can lead to spastic paraplegia, including cerebral palsy, brain injury, spinal cord infection, spinal cord tumor, and spinal cord injury[22-26]. Among them, the most common cause of spastic paraplegia in children is cerebral palsy, which can mimic HSP[27].…”

Villonodular synovitis of the lumbar spine: Case report of a rare pathology

“…The diffuse form is usually monoarticular, affecting large joints such as knees, hips, ankles, shoulders, and elbows 1,4 . But PVNS rarely involves the axial skeletal system 5‐7 . Within the spine, lumbar localizations are the less encountered.…”

“…1,4 But PVNS rarely involves the axial skeletal system. [5][6][7] Within the spine, lumbar localizations are the less encountered. Thus, their description in the literature is only restricted to some case reports.…”