Pigmented purpuric dermatoses: An overview

Abstract

Pigmented purpuric dermatoses are a spectrum of disorders characterized by a distinct purpuric rash, mainly localized to the lower limbs, which are morphologically dissimilar but histopathologically indistinguishable. Their etiology remains obscure. They are rather resistant to treatment. Although diagnosed quite straightforwardly, the disease entity remains an enigma and a therapeutic challenge. The current narration discusses the outline of the epidemiology, etiopathogenesis, clinical features, histopathology and management of these disorders. The current review, hopefully, may once again rekindle interest in the entity, for it has been sparingly reported or discussed for the benefit of under- and/or postgraduates and those in practice, including family physicians.

Gardner-Diamond syndrome associated with complex regional pain syndrome

“…7 Schamberg's disease is a form of pigmented purpuric dermatoses and is classically described as having a "cayenne pepper" like appearance with pinhead sized reddish puncta that coalesce to form areas of orange or brown pigmentation. 8 However, any other type of purpuric lesion or GDS associated with CRPS has not been previously reported in the literature. There has been brief mention that CRPS and GDS maybe associated conditions.…”

Multiple Red-Brown Macules in Legs of a Child

“…[1][2][3][4] An cakço cuk ol gu larbü yükoran daspon taniyi leş megös ter mek te dir. 5 Bi zimol gu muz da dalez yon larti piklo ka li zas yonolanalteks tre mi te le reyer leş mek lebir lik te ol gu mu zunya şıbek le nen denda hagenç ti.…”

“…1,3,5 Genç ya şıne de niy lelez yon la rınken di li ğin denge ri le me ora nıyük sekol du ğun danhas ta mızte da vi sizta ki be alın dı.…”

Schamberg disease: uncommon reaction to a common drug

“…1 Histology shows superficial perivascular infiltration of lymphocytes, and rarely macro phages, associated with endothelial swelling and luminal narrowing, variable degrees of hemosiderin deposition, but no evidence of vasculitis. 1,2 Drugs are important precipitating factors for Schamberg disease, with acetaminophen the most commonly implicated drug. 2,3 Unlike the idiopathic form of Schamberg disease, most drug-induced cases resolve quickly after the offending drug is stopped.…”

“…1,2 Drugs are important precipitating factors for Schamberg disease, with acetaminophen the most commonly implicated drug. 2,3 Unlike the idiopathic form of Schamberg disease, most drug-induced cases resolve quickly after the offending drug is stopped. 3 In our patient, the eruption gradually cleared over several weeks after the acetaminophen was stopped.…”