Pigmented Pre-malignant and Malignant Lesions of Skin with Special Reference to Atypical Presentations

Shirazi, Nadia; Jindal, Rashmi; Singh, Sneha; Harsh, Meena; Ahmad, Sohaib

doi:10.7860/jcdr/2015/13245.6226

Cited by 1 publication

(1 citation statement)

References 16 publications

(2 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Microscopically in nodular melanomas, asymmetry in size, shape, pigmentation of the nodules can be noted at a cytological level. Clarks grading was done and the majority of the lesions were Grade V. Similar studies done by "Shirazi et al" 17 showed most of the lesions in occuring in Clarks Grade III and IV.…”

Section: Discussionmentioning

confidence: 58%

A histo-pathological study with an emphasis on stratification of pigmented lesions of the skin

Anand¹,

Ilanthodi²,

N³

et al. 2020

IJPO

View full text Add to dashboard Cite

Pigmented lesions can be close mimickers of melanoma and clinically challenging to diagnose. These can be melanocytic or non-melanocytic pigmented disorders. Pigmented lesions are close mimickers of melanoma and histopathology is a cornerstone for diagnosing these lesions. 1.To study the histomorphological patterns of pigmented lesions of the skin; 2. To categorise and differentiate pigmented lesions from melanoma based on histomorphology.A total of 70 histologically diagnosed cases of pigmented lesions of the skin were retrospectively studied from January 2018 to December 2019 in department of Pathology, of a Tertiary care center, Mangalore (India). Clinically suspicious skin lesions were taken up for the study. Sections from the skin punch biopsies and wide excision of the lesion were processed, stained with Hematoxylin and Eosin stain and studied for its histomorphological features.Out of the 70 cases studied, 22 cases were melanocytic lesions including 12 cases of Malignant melanoma (17.1%), Benign Naevi- 10 cases (14.2%) and 48 cases were non-melanocytic lesions including Lichen planus- 30 cases (42%), Seborrheic keratosis- 10 cases (14.3%), Basal cell carcinoma- 8 cases (11.4%).The pigmented lesions are categorised into melanocytic and non melanocytic lesions for a better understanding. Among the Melanocytic lesions, our study witnessed predominantly cutaneous melanoma. And in non melanocytic lesions lichen planus predominated.

show abstract

Section: Discussionmentioning

confidence: 58%