Pigmented Nevus of the Fingernail Matrix

Noble, John F.; Ferrin, Allen; Merandino, K. A.

doi:10.1001/archderm.1952.01530200053007

Cited by 16 publications

(4 citation statements)

References 3 publications

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“…In the minds of many physicians, the automatic association of pigmented streaks and periungual hyperpigmentation with melanoma may lead to unnecessarily radical surgery. The patient of Noble et al 28 had only melanonychia striata, yet an amputation was performed of the distal phalanx of the involved thumb; the patient was a young physician and the lesion proved to be a subungual junctional nevus.…”

Section: Discussionmentioning

confidence: 99%

Periungual Hyperpigmentation Mimicking Hutchinson's Sign Associated with Minocycline Administration

Mooney

Bennett

1988

The Journal of Dermatologic Surgery and Oncology

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An assessment of the occurrence rate of periungual hyperpigmentation with subungual melanoma (Hutchinson's sign) and periungual hyperpigmentation with other subungual lesions has not been published, although periungual hyperpigmentation with a pigmented streak or other pigmented lesion of the nail has been considered pathognomonic for subungual melanoma for a century. We report a case of minocycline hyperpigmentation presenting as a longitudinal pigmented streak of the nail associated with periungual hyperpigmentation. These pigmentary changes could be mistaken for Hutchinson's sign.

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Section: Discussionmentioning

confidence: 99%

Periungual Hyperpigmentation Mimicking Hutchinson's Sign Associated with Minocycline Administration

Mooney

Bennett

1988

The Journal of Dermatologic Surgery and Oncology

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“…Some authors suggest prophylactic excision of nevocytic nevi of the nails, especially those that have been congenital (7,9). In the past, some physicians even advocated amputation of the terminal phalanx of the affected digit (7,23). Noble et al (23) reported a 24‐year‐old physician who had longitudinal melanonychia of the left fifth fingernail of 4‐years duration.…”

Section: Discussionmentioning

confidence: 99%

“…In the past, some physicians even advocated amputation of the terminal phalanx of the affected digit (7,23). Noble et al (23) reported a 24‐year‐old physician who had longitudinal melanonychia of the left fifth fingernail of 4‐years duration. After he had been evaluated by several consultants in dermatology, surgery, and pathology, the consensus was to eliminate the lesion by amputation of the terminal phalanx of the affected finger.…”

Section: Discussionmentioning

confidence: 99%

A Subungual Nevus in a Filipino Child

Leung

Woo

2004

Pediatric Dermatology

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A 2.5-year-old Filipino girl with a progressively growing, black, subungual lesion is described. A biopsy was performed because of the progressive increase in size of the lesion and its periungual involvement. Histologic examination revealed a junctional nevus. To our knowledge, this represents the first report of subungual nevus in a Filipino child. The need for histologic diagnosis prior to definitive surgery cannot be overemphasized.

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“…It is well known that a primary malignant melanoma may develop in the nail matrix and produce a pigment streak in the nail plate. A similar streak may be caused by a benign junctional naevus in the nail matrix (Noble, Ferrin & Merandino, 1952)-Less well-defined streaks arc very common in coloured persons and arc due to the presence of dopa-positive melanocytes without amounting to a true naevus (Leyden & Spott, 1972). It is much less well known that secondary deposits of malignant melanoma in the nail matrix may produce deeply pigmented bands in the nail plate.…”

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confidence: 99%