Pigmented gingival cyst

Pigmented ameloblastic fibrodentinoma: a novel melanin-pigmented intraosseous odontogenic lesion

“…The review of the English language literature yields 30 well-documented cases of pigmented odontogenic tumors (Table 1): 18 were calcifying odontogenic cysts, three were adenomatoid odontogenic tumors, three were ameloblastic fibro-odontomas, two were odontomas, one was an odonto-ameloblastoma, one was an ameloblastic fibroma, one was an odontogenic fibroma, and one was an unclassified tumor (calcifying epithelial odontogenic tumor by author's suspicion). Only 12 cases of pigmented odontogenic cysts have been documented: eight were odontogenic keratocysts [4,5,19,31], and there was one gingival cyst [12], one botryoid odontogenic cyst [3], one lateral periodontal cyst [6], and one dentigerous cyst [41]. Melanocytes and/or melanin pigment in these reported odontogenic lesions were microscopically observed and macroscopically showed no pigmentation, except for two cases [25,41] with macroscopically visible mild pigmentation.…”

Gingival Cyst of the Adult: Regenerative Therapy of Associated Root Exposure. A Case Report and Literature Review

“…Including the present report, only 24 cases 10,13,14,18,28,31,34,35,[39][40][41]44 mentioned follow-up of the lesions, and none reported recurrence; the specifically defined follow-up period, provided in only 19 cases, 10,13,18,28,31,34,40,41 including the present report, ranged from 1 month to 3 years, with the average time being 1.2 years. Only the present case and Holder and Kunkel 10 reported radiographic follow-up, with both reports indicating almost complete resolution of the associated hard tissue defects.…”

“…Our review of the literature identified 155 reported cases of gingival cysts (Table 1). 5–48 The outward appearance of a GCA was typically an oval to round, firm, elevated swelling located on the attached gingiva and/or the alveolar mucosa. Most were ∼5 mm in diameter, but some lesions were >1 cm.…”

“…27,35,45 Other variants included respiratory epithelium lining the cyst cavity 21 and pigmented melanocytes interspersed throughout the cystic epithelium. 13 The lumen of the cyst was most often empty, but keratin or amorphous eosinophilic material was reported, 26,38,44 including an isolated case of calcified material in the lumen. 44 Cysts presenting in the gingiva were either of nonodontogenic or odontogenic origin.…”

“…Bhaskar and Laskin 8 were the first to report the GCA as distinct, clinically and radiographically perceptible oral lesions, and presented three cases that highlighted specific characteristics. Their report, 8 along with other subsequent reports, [9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27] provided enough evidence for the lesion to gain acceptance as an individual entity in the wide spectrum of cystic pathology that can potentially occur in the oral cavity. 1 The aim of this report was to present a case of GCA treated with a combined regenerative approach to address the lesion-associated hard tissue defect and the excisional biopsy-associated soft tissue defect.…”