Pigmentation level of human iPSC-derived RPE does not indicate a specific gene expression profile
Yoko Nakai-Futatsugi,
Jianshi Jin,
Taisaku Ogawa
et al.
Abstract:Retinal pigment epithelium (RPE) cells show heterogeneous level of pigmentation when cultured in vitro. To know whether their color in appearance indicates functional qualities of the RPE, especially in terms of clinical use for cell transplantation, we analyzed the correlation between the color intensities and the gene expression profile of human-induced pluripotent stem cell-derived RPE cells (iPSC-RPE) at single cell level. For this purpose, we utilized our recent invention, Automated Live imaging and cell … Show more
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