Pigmentary Changes in Acquired Retinoschisis

Senile retinoschisis versus retinal detachment, the additional value of peripheral retinal OCT scans (SL SCAN‐1, Topcon)

“…Typical is the relative immobility of this inner layer compared with a retinal detachment. A smooth or bullous elevation is also seen in retinal detachments, but characteristics for a (longer standing) retinal detachment are retinal pigment alterations and demarcation lines (Straatsma 1980; Byer 1986; DiSclafani et al. 1988).…”

“…2007). Diagnosis is based on the characteristic biomicroscopic signs: the appearance of microcystoid degeneration of the neurosensory retina, forming a relatively immobile transparent smooth or bullous elevation of the inner layer wall, and minimal pigment alterations or atrophy of the retinal pigment epithelium layer (RPE; Foos 1970; Byer 1986; DiSclafani et al. 1988; Madjarov et al.…”

Use of Spectral-Domain Optical Coherence Tomography to Differentiate Acquired Retinoschisis From Retinal Detachment in Difficult Cases

“…However, schisis detachments whereby there is redistribution of fluid from within the schisis cavity to cause a detachment of the outer leaf that remains contained within the initial area of schisis may result in a pigmented demarcation line causing some confusion in the diagnosis. 4 In RS, because of the disruption in the connections between the inner and outer retinal layers, an absolute scotoma is present in the area of schisis. 5 Clinical tests such as indirect perimetry or slit-lamp spot perimetry use this clinical feature and can be a useful test to help distinguish between the two.…”

Infantile presentation of X linked retinoschisis.

“…Causes of bilateral retinal elevation in infancy TraumaRetinopathy of prematurity Optic disc coloboma discussion of paper by Grenen et al 15); histologically, pigment lines represent retinal pigment epithelial cell hyperplasia and in order for pigment cells to migrate into the schisis cavity there would have to be either a retinal detachment or an outer leaf break present [25][26][27]. In this series outer leaf breaks were identified only in case 2, but vitreous and intraschisis haemorrhage may have precluded a clear view of the outer leaf of the schisis cavity in other cases.…”