Pigment Red 60 micronization using supercritical fluids based techniques

Study on Precipitation of Astaxanthin in Supercritical Fluid

“…The drug particle with a controlled particle size (PS) and particle size distribution (PSD) can deposit in the human respiratory tract selectively, which will maximize their effectiveness and minimize the adverse side effects [4]. The use of very small pigment particles can improve first of all the stability of pigment in the dispersion medium, but also the color strength, contrast, and transmittance can be enhanced [5]. Therefore, many researchers keep an increasingly interest in decreasing the size of drug particles.…”

Ultra-fine particles formation of C.I. Pigment Green 36 in different phase regions via a supercritical anti-solvent process

“…The precipitation kinetic parameters of Pigment Blue 15:6 were determined with the aid of the population balance theory [6]. Reverchon et al [7] investigated micronization of C.I. Disperse red 60 using both SAS and supercritical-assisted atomization (SAA) methods.…”

Phase equilibrium data for the ternary system (propane + chloroform + oryzanol)

“…As mentioned in the literature, when precipitation takes place below the mixture critical point, within two-phase region, the precipitated particles can exhibit different morphology and higher size than those precipitated above the mixture critical point, in which super-saturation levels arise, affording smaller particles [11,14,15]. Also, the phase behaviour of solvent/anti-solvent system may change in the presence of solute, due to the elevation of the mixture critical point [6,16].…”