Pigeon-Breeder’s Disease

Hansen, P J; Penny, Ronald

doi:10.1159/000231244

Cited by 87 publications

(1 citation statement)

References 2 publications

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“…In chronic BFL specific antibodies against pigeon or budgerigar dropping extracts were positive in 87% of the recurrent form and 35% of the insidious cases, while antigen-induced lymphocyte proliferation was positive in more than 90% of both groups [46]. Antigen-induced lymphocyte proliferation is also useful in differentiating subjects with HP from asymptomatic exposure [81,82]. …”

Section: Introductionmentioning

confidence: 99%

Management of hypersensivity pneumonitis

Agache

Rogozea

2013

Clinical & Translational All

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Hypersensitivity pneumonitis (HP) is an interstitial lung disease due to a combined type III and IV reaction with a granulomatous inflammation, caused by cytotoxic delayed hypersensitivity lymphocytes, in a Th1/Th17 milieu, chaperoned by a deficient suppressor function of T regulatory cells. Skewing toward a Th2 phenotype is reported for chronic HP. Phenotypic expression and severity depends on environmental and/or host genetic and immune co-factors. The wide spectrum of causative antigens is continuously up-dated with new sources of airborne organic particles and drug-induced HP. The diagnosis requires a detailed history, measurement of environmental exposure, pulmonary function tests, imaging, detection of serum specific antibodies, broncho-alveolar lavage, antigen-induced lymphocyte proliferation, environmental or laboratory-controlled inhalation challenge and lung biopsy. Complete antigen avoidance is the best therapeutic measure, although very difficult to achieve in some cases. Systemic steroids are of value for subacute and chronic forms of HP, but do not influence long term outcome. Manipulation of the immune response in HP holds future promise.

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Section: Introductionmentioning

confidence: 99%

Management of hypersensivity pneumonitis

Agache

Rogozea

2013

Clinical & Translational All

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Metalworking fluid-associated hypersensitivity pneumonitis: A workshop summary

1997

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A workshop discussing eight clusters of hypersensitivity pneumonitis in the automotive industry among metalworking fluid‐exposed workers concluded that a risk exists for this granulomatous lung disease where water‐based fluids are used and unusual microbial contaminants predominate. Strong candidates for microbial etiology are nontuberculous mycobacteria and fungi. Cases of hypersensitivity pneumonitis occur among cases with other work‐related respiratory symptoms and chest diseases. Reversibility of disease has occurred in many cases with exposure cessation, allowing return to work to jobs without metalworking fluid exposures or, in some situations, to jobs without the same metalworking fluid exposures. Cases have been recognized with metalworking fluid exposures generally less than 0.5 mg/m3. The workshop participants identified knowledge gaps regarding risk factors, exposure‐response relationships, intervention efficacy, and natural history, as well as surveillance needs to define the extent of the problem in this industry. In the absence of answers to these questions, guidance for prevention is necessarily limited. Am. J. Ind. Med. 32:423ndash;432, 1997. © 1997 Wiley‐Liss, Inc.

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Hypersensitivity Pneumonitis (Extrinsic Allergic Alveolitis)

Barrios

2008

Dail and Hammar’s Pulmonary Pathology

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Pigeon-Breeder’s Disease

Cited by 87 publications

References 2 publications

Management of hypersensivity pneumonitis

Management of hypersensivity pneumonitis

Metalworking fluid-associated hypersensitivity pneumonitis: A workshop summary

Hypersensitivity Pneumonitis (Extrinsic Allergic Alveolitis)

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