Piezoelectric Resonances in Amino-acids

Vasilescu, D.; Cornillon, R.; Mallet, G.

doi:10.1038/225635a0

Cited by 47 publications

(27 citation statements)

References 6 publications

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“…Amino acids are capable of forming 3D crystal structure, and if the crystal of the amino acid belongs to the so‐called 20 piezoelectric crystal classes, can exhibit piezoelectric properties, like other crystals 54. In 1970, Vasilescu et al investigated the piezoelectricity in various amino acids 55. They analyzed the piezoelectric property of amino acids crystals of different structures, such as left‐handed ( l ), right‐handed ( d ), and dl structures ( dl amino acids contain both l ‐ and d ‐amino acids and are termed racemic mixtures) using nuclear quadrupole resonance spectrometer, and compared with theoretical predictions.…”

Section: Piezoelectricity Of Amino Acidsmentioning

confidence: 99%

“…Most amino acids exist in a chiral symmetric group, l or d form, and thus exhibit a piezoelectric response. Generally these chiral symmetric group crystals allow shear piezoelectric tensors, d 14 , d 25 , and d 36 , but no longitudinal piezoelectric tensors such as d 11 , d 22 , and d 33 55–61. However, the longitudinal piezoelectric tensor in piezoelectric materials is significantly important, and has great advantages for practical piezoelectric applications, because most of the environmentally available types of mechanical forces are of compressive or tensile direction.…”

Section: Piezoelectricity Of Amino Acidsmentioning

confidence: 99%

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Biomolecular Piezoelectric Materials: From Amino Acids to Living Tissues

et al. 2020

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Biomolecular piezoelectric materials are considered a strong candidate material for biomedical applications due to their robust piezoelectricity, biocompatibility, and low dielectric property. The electric field has been found to affect tissue development and regeneration, and the piezoelectric properties of biological materials in the human body are known to provide electric fields by pressure. Therefore, great attention has been paid to the understanding of piezoelectricity in biological tissues and its building blocks. The aim herein is to describe the principle of piezoelectricity in biological materials from the very basic building blocks (i.e., amino acids, peptides, proteins, etc.) to highly organized tissues (i.e., bones, skin, etc.). Research progress on the piezoelectricity within various biological materials is summarized, including amino acids, peptides, proteins, and tissues. The mechanisms and origin of piezoelectricity within various biological materials are also covered.

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Section: Piezoelectricity Of Amino Acidsmentioning

confidence: 99%

Section: Piezoelectricity Of Amino Acidsmentioning

confidence: 99%

Biomolecular Piezoelectric Materials: From Amino Acids to Living Tissues

et al. 2020

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“…studied, which includes glycine, tyrosine, tryptophan, aspartic acid, histidine, cystine and serine, the activation energy for reorientation of the NH 3 + group (ranging from 28.6 to 40.0 kJ mol À1 ) shows the highest value for DL-serine, suggesting that the barriers are, to a large extent, intermolecular in origin and depend on details of the packing, H-bonding and electrostatic interactions [22]. On the other hand, Vasilescu et al [20] found that, contrarily to what could be expected based on the crystal structure of DL-serine, this compound shows piezoelectricity. Such finding could be interpreted as an indication of a more complex H-bond structure in crystalline DL-serine than apparent in the X-ray experiments.…”

Section: Introductionmentioning

confidence: 99%

“…These studies include the NQR study of Vasilescu et al [20], who investigated piezoelectricity in several amino acids crystals, including DL-serine, and the solid state NMR studies of Reuveni (ENDOR; T = 4.2 K; single partially deuterated DL-serine crystal [21]) and of Andrew et al…”

Section: Introductionmentioning

confidence: 99%

Low-temperature infrared spectra and hydrogen bonding in polycrystalline dl-serine and deuterated derivatives

Jarmelo

Reva

Rozenberg

et al. 2006

Vibrational Spectroscopy

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The FT-IR spectra of polycrystalline DL-serine [a-amino-b-hydroxypropionic acid; HO-CH 2 -CH(NH 3 ) + -COO À ] and isotopically substituted [ND/OD Alcohol (<10% and >90% D); CD 2 (>98% D)] DL-serine were recorded in the range 4000-500 cm À1 in the temperature range 300-10 K, and fully assigned. The isotopic-doping/low-temperature methodology, which allows for decoupling of individual proton vibrational modes from the crystal bulk vibrations, was used to estimate the energies of the different H-bonds present in DL-serine crystal. To this end, the frequency shifts observed in both the NH/OH stretching and out-of-plane bending spectral regions (relatively to reference values for these vibrations in nonhydrogen-bonded DL-serine molecules) were used, together with previously developed empirical correlations. The results are compared with available structural data on this amino acid. #

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“…In particular, we emphasize the fact that almost all the amino-acid residues that compose enzyme molecules exhibit piezoelectricity (11) and that many proteins behave like semiconductors (12).…”

mentioning

confidence: 99%

Piezoelectric Theory of Enzymic Catalysis as Inferred from the Electromechanochemical Principles of Bioenergetics

Caserta¹,

Cervigni²

1974

Proc. Natl. Acad. Sci. U.S.A.

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Starting from the electromechanochemical principles of bioenergetics formulated by Green and Ji, a theory is proposed which describes enzymic catalysis in terms of piezoelectricity in semiconductors. The choice of this particular physical effect for describing catalytic processes is founded on the following experimental observations: most of the amino-acid residues of enzymes, as well as a large number of other biologically important molecules, exhibit piezoelectric resonances; besides, enzymes can behave like semiconductors. In the proposed theory the catalysis is assumed to be accomplished by means of three fundamental processes: (a) the lowering of the substrate-product energy barrier; (b) the electroninduced selective amplification of the low-frequency vibrational waves present in thermal background in the enzyme structure; and (c) the channeling into the substrate of the energy associated with the amplified waves and utilization of this energy for generating electrical or mechanical fields inside a susceptible region of the substrate. A mathematical description of the theory is outlined, and a rough estimate of some quantities involved in the process of wave amplification is also reported.The search for a unitary principle underlying enzymic catalysis is one of the most intriguing problems of contemporary biology (1, 2). Many models have been proposed for explaining enzyme catalytic power and enzyme specificity, but, as Reiner properly observed (3), the proposed theories are partial in that none of them embraces all the known facts in the framework of a unified treatment.The electromechanochemical (EMC) theory of bioenergetic processes, recently formulated by Green and Ji (4-7), is a wellordered set of principles which, when applied to the enzymic catalysis, provide a powerful tool for the overcoming of any partial view about the catalytic processes.Limitations of space prevent us from discussing those principles extensively; therefore, we shall only mention three fundamental concepts upon which the EMC theory is based. First, enzymes are visualized as macromolecular devices that episodically and impermanently convert thermal energy of the environment into EMC potential energy of the enzymic system. Second, the EMC energy is directed to the polarization of a susceptible bond of the substrate and is used for this purpose within the lifetime of the energized state. Third, enzymes possess a high informational content by means of Abbreviations: EMC, electromechanochemical; PE, piezoelectric. t Present address: Divisione Applicazioni Radiazioni, C. S. N.Casaccia, Casella Postale 2400, 00100 Roma, Italy. 4421 which all the maneuvers enabling the substrate-product conversion are controlled; this informational content is expressed by the concept of negative entropy, which measures the nonstatistical order of living systems.The intrinsic physical nature of the EMC theory prompted us to explore the possibility of rationalizing enzymic catalysis in terms of some solid-state physics phenomena with the main...

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Piezoelectric Resonances in Amino-acids

Cited by 47 publications

References 6 publications

Biomolecular Piezoelectric Materials: From Amino Acids to Living Tissues

Biomolecular Piezoelectric Materials: From Amino Acids to Living Tissues

Low-temperature infrared spectra and hydrogen bonding in polycrystalline dl-serine and deuterated derivatives

Piezoelectric Theory of Enzymic Catalysis as Inferred from the Electromechanochemical Principles of Bioenergetics

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