Picobirnavirus: A Putative Emerging Threat to Humans and Animals

Kattoor, Jobin Jose; Sircar, Shubhankar; Saurab, Sharad; Shanmuganathan, S; Dhama, Kuldeep; Malik, Yashpal Singh

doi:10.14737/journal.aavs/2016/4.6.327.331

Cited by 4 publications

(3 citation statements)

References 26 publications

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“…There are two genogroup (I and II) circulating throughout the world. Evidence are available on high genetic relatedness between human and porcine PBVs, human and equine PBVs and, human and rodents PBVs, suggesting extant crossing points in the ecology and evolution of heterologous PBV strains (Malik et al, 2014b;Kattoor et al, 2016). Very recently, Picobirnavirus has also been detected in dogs and bats, Vervet monkeys, wolves (Conceicao-Neto et al, 2016) on the basis of complete genome sequence 2.…”

Section: Picobirnavirusesmentioning

confidence: 99%

Enteric Viral Zoonoses: Counteracting Through One Health Approach

Verma¹,

Bhat²,

Sircar³

et al. 2018

JEBAS

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Zoonotic viruses own a strong capability of transmission from animals to human or vice-versa, making them more resilient to quick modifications in their genetic sequences. This provides the advantage to adapt the new changes for better survival, increasing pathogenicity and even learning ability to jump species barriers. Usually, zoonotic viral infections involve more than one host which make them more serious threat to the surrounding inter-genus species. Zoonotic infection also helps in understanding the evolutionary course adopted by the causative virus. The virus sequence based phyloanalysis has given better methods for comparative evaluation of the viral genomes in the probability of transmissions and diversity. Several animal hosts have been identified as reservoirs and for their potential zoonotic transmission abilities. The early and accurate diagnosis of emerging and re-emerging zoonotic viruses becomes inevitable to restrict and to establish correlation with the spread of these viral infections in different milieus. For the in-depth understanding of the prevailing, emerging/ or re-emerging zoonotic enteric viral infections apposite surveillance programmes would be more meaningful in curbing the virus dispersal. There is a need to gather sound scientific information on these pathogens including their reservoir hosts, immunopathology, and genetic diversity. The implementation of relevant public health

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Section: Picobirnavirusesmentioning

confidence: 99%

Enteric Viral Zoonoses: Counteracting Through One Health Approach

Verma¹,

Bhat²,

Sircar³

et al. 2018

JEBAS

Self Cite

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“…PBVs are mostly bi-segmented, double-stranded RNA viruses, classified under the Picobirnaviridae family (Delmas et al, 2019 ) . Segment 1 (L gene) has an RNA structure 2.2 to 2.7 kbp in length and encodes viral capsid proteins, while the 1.2–1.9 kbp segment 2 (S gene) expresses RNA-dependent RNA polymerase (RdRp), which is crucial for genome replication (Kattoor et al, 2016 ; Malik et al, 2017 ). Recently, efforts have been made to characterise the highly divergent family Picobirnaviridae, and segment 2-based classification has been the most widely utilised approach (Knox et al, 2018 ).…”

Section: Introductionmentioning

confidence: 99%

Genetic diversity, frequency and concurrent infections of picobirnaviruses in diarrhoeic calves in Turkey

Atasoy

Işidan

Turan

2022

Trop Anim Health Prod

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Calf diarrhoea is one of the major problems in cattle farming with high morbidity and mortality in herds. Two enteric viruses, bovine rotavirus (BRV) and bovine coronavirus (BCoV), are the leading cause of gastroenteritis in young calves, whereas picobirnaviruses (PBVs) are often associated with diarrhoea. In the present study, the faecal specimens of 127 diarrhoeic bovines (less than 1-month-old) were employed to investigate the infection frequencies of these three pathogens. Results indicated that frequencies of BRV and BCoV in diarrhoeic calves were 38.58% and 29.92%, respectively. The 7.08% of bovine calf samples (9 out of 127) were found to be positive for PBV genogroup I. Sequence analysis further revealed the high genetic heterogeneity within representative PBV sequences. Additionally, both PBV-BCoV ( n = 2) and BCoV-BRV-PBV ( n = 1) co-infections were detected in bovine calves for the first time. Consequently, our findings pointed out the highly divergent nature of PBVs without regard to exact host or territory and the occasional co-existence with other enteric agents.

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“…There are several causes for the emergence of enteric viruses, which account for over 100 viruses, including re-emerging, emerging, and novel pathogens that affect animals and/or humans at various stages of their lives. Acute gastroenteritis is caused by viruses such as enteric Coronaviruses, Bocavirus, Kobuvirus, Rotavirus as well as later recognized viruses such as Picobirnavirus (PBV) [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

Picobirnaviruses in animals: a review

et al. 2022

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Picobirnaviruses (PBVs) are small non enveloped viruses with bi-segmented ds RNA. They have been observed in a wide variety of vertebrates, including mammals and birds with or without diarrhoea, as well as in sewage samples since its discovery (1988). The source of the viruses is uncertain. True hosts of PBVs and their role as primary pathogens or secondary opportunistic agents or innocuous viruses in the gut remains alien. The mechanisms by which they play a role in pathogenicity are still unclear based on the fact that they can be found in both symptomatic and asymptomatic cases. There is a need to determine their tropism since they have not only been associated with viral gastroenteritis but also been reported in the respiratory tracts of pigs. As zoonotic agents with diverse hosts, the importance of epidemiological and surveillance studies cannot be overstated. The segmented genome of PBV might pose a serious public health issue because of the possibility of continuous genetic reassortment. Aware of the growing attention being given to emerging RNA viruses, we reviewed the current knowledge on PBVs and described the current status of PBVs in animals.

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Picobirnavirus: A Putative Emerging Threat to Humans and Animals

Cited by 4 publications

References 26 publications

Enteric Viral Zoonoses: Counteracting Through One Health Approach

Enteric Viral Zoonoses: Counteracting Through One Health Approach

Genetic diversity, frequency and concurrent infections of picobirnaviruses in diarrhoeic calves in Turkey

Picobirnaviruses in animals: a review

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