Phytotoxic activity and conformational analysis of thymol analogs from Hofmeisteria schaffneri☆

Antinociceptive effect of extracts and compounds from Hofmeisteria schaffneri

“…After filtration, the extract was concentrated in vacuo to yield 172 g of a greenish residue. Hofmeisterin III (1) (100 mg), thymol (2) (79 mg), and 8,9-epoxy-10-acetoxythymyl angelate (3) (20 mg) were isolated as previously described (Pérez-Vásquez et al, 2008).…”

“…The spectral properties of 4 and 5 were identical to those described by Mathela (Mathela et al, 2008). Compounds 1-3 were isolated from the plant material as previously described (Pérez-Vásquez et al, 2008). Compound 1 (0.1-17 mg/kg) was the most active increasing significantly the latency to thermal stimulis in a dose dependent manner up to the dose of 1 mg/kg.…”

Phytotoxic compounds from roots ofCentaurea diffusaLam.

“…Our results showed that 2 decreased the fresh weight of A. thaliana seedlings by 70% even at 50 μg/ml and caused significant bleaching of the seedlings at phytotoxic concentrations. A bleaching effect has been reported for monoterpene derivatives isolated from another Asteraceae species plant family 22 and they were shown to be inhibitors of phytoene desaturase, a key enzyme in carotenoid pigment biosynthesis. Since carotenoids protect chlorophyll from photooxidation, their lack would result in loss of chlorophyll.…”

Antimicrobial activity and chemical composition of the essential oil of Hofmeisteria schaffneri

“…Hofmeisteria schaffneri (A. Gray) R. M. King & H. Robinson (Asteraceae), commonly known as ambar, is an aromatic evergreen medicinal herb, which grows naturally in the oak and pine–oak forested mountains of the central Mexican states of Jalisco and San Luis Potosi [1,2] . Hofmeisteria schaffneri is cultivated in domestic gardens in Mexico City and the states of Mexico and Michoacán.…”

“…Hofmeisteria schaffneri is cultivated in domestic gardens in Mexico City and the states of Mexico and Michoacán. The fresh or dried herb is available in Mexican markets and commonly used by local people for treating stomach aches, skin infections and fevers [2,3] . Previous investigations on the organic (CH 2 Cl 2 ‐MeOH 1 : 1) and aqueous extracts from the aerial parts of the plant yielded several thymol analogs, including compounds 1–10, which possess phytotoxic and antinociceptive properties [1–3] …”