Phytotherapy in obstetrics – therapeutic indications, limits, and dangers

Grigoriu, Corina; Varlas, Valentin; Călinescu, Gina; Bălan, Andra Magdalena; Bacalbaşa, Nicolae; Gheorghe, Consuela-Mădălina; Salmen, Teodor; Zugravu, Corina Aurelia; Bohîlțea, Roxana Elena

doi:10.25122/jml-2021-0353

Cited by 6 publications

(6 citation statements)

References 28 publications

(30 reference statements)

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“…19 It has been reported in a systematic review that linden-containing teas affect the neurovegetative system and are beneficial in cases of insomnia and anxiety. 20 It is stated that ginger is one of the most widely used natural products consumed as a spice and medicine in the treatment of inflammation and insomnia. Increasing evidence reveals that ginger has a wide range of biological activities, particularly anti-inflammatory and insomnia effects.…”

Section: Discussionmentioning

confidence: 99%

“…It has also been reported that thyme can be used to relieve rheumatic pains 19. It has been reported in a systematic review that linden-containing teas affect the neurovegetative system and are beneficial in cases of insomnia and anxiety 20. It is stated that ginger is one of the most widely used natural products consumed as a spice and medicine in the treatment of inflammation and insomnia.…”

Section: Discussionmentioning

confidence: 99%

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Complementary and Alternative Medicines Used by Individuals With Rheumatological Diseases to Cope With Sleeplessness

Tuna

Hakbilen

Yılmaz

2022

Holistic Nursing Practice

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This study aims to determine complementary and alternative medicine methods used by rheumatology patients to cope with insomnia and to evaluate their attitudes toward complementary and alternative medicine methods. This descriptive study was completed with 167 patients followed up by the rheumatology unit of a university hospital. Data were collected with the patient identification form and the Holistic Complementary and Alternative Medicine Questionnaire. The mean age of the participants was 44.76 ± 8.96 years and the mean disease duration was 52.90 ± 35.51 months. Most of the participants (69.5%) were women, with 64.1% primary school graduates. Majority of the participants (96.4%) knew complementary and alternative medicine methods, and the main source of information (51.5%) was the internet and social media. The most frequently applied method was phytotherapy (58.7%), the most frequently used plant (30.5%) was stinging nettle and the mean Holistic Complementary and Alternative Medicine Questionnaire score of the patients was 26.68 ± 3.51. Rheumatology patients frequently use complementary and alternative medicine methods to cope with insomnia symptoms and the most commonly used complementary and alternative medicine method used by patients is phytotherapy.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Complementary and Alternative Medicines Used by Individuals With Rheumatological Diseases to Cope With Sleeplessness

Tuna

Hakbilen

Yılmaz

2022

Holistic Nursing Practice

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“…However, in Spain and the United States, only 14.2% and 13% of women, respectively, use CM methods. The use of CM methods is also low in countries with weak economies, such as Kenya [20,22]. In the majority of countries worldwide, herbal remedies are classifi ed as over-the-counter drugs.…”

Section: Relevancementioning

confidence: 99%

Characteristics of Phytotherapeutic Use During Pregnancy and in the Postnatal Period: Indications, Limitations, and Risks (Literature Review and Original Research)

Voloshyn,

Voloshina,

Dogolich

et al. 2023

Neonatol. hìr. perinat. med.

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Increase in the morbidity of women during pregnancy and in the postnatal period, the known limitations using of modernsynthetic drugs cause the search for ways of medical assistance, in particular use of phytotherapy.Aim: highlight the world and own experience of using phytotherapeutic agents during pregnancy and in the postnatal period,indications, limitations and threats. Materials and methods: used available monographic and journal sources in the electronic systems MED Line, EMBASE, Scopus, Web of Science using methods of analysis, comparison and generalization.Results. It has been established that scientists from the world’s leading scientifi c centers state a growing interest in using ofphytotherapy methods as one of the important approaches of medical pluralism in the pathology of pregnancy and in the postnatal period. depending on the level of economic development and the state of the medical industry of the state and the commonality and diff erences of the principles and forms of providing phytotherapeutic assistance. Commonality is that even ancient and simple methods and means of phytotherapy in this contingent of patients, along with modern ones in developed countries, are, albeit to varying degrees, eff ective and safe.In countries with a low socio- ecological level, simple methods according to ancient traditions are still forced to be used,mainly as a self-initiative or on the advice of friends, family, rarely – on the recommendations of specialists without clearrecommendations regarding the duration and remote consequences of application, which is unfavorable.There are some diff erence between of using phytotherapy in the developed countries of Europe and USA is that variousmeans, forms of plant factors are mainly manufactured in accordance with modern requirements of the Ministry of Health, arerecommended on the basis of evidence- based medicine by properly trained obstetrics and gynecology personnel, modern sources of information are available for the improvement of medical personnel, training of pregnant women. The clear eff ectiveness and side eff ects of herbal preparations, their impact on the body of the mother, fetus and lactation processes are monitored.Various trainings and forms of improving using of herbal medicines are carried out and need for close contacts of obstetriciangynecologists with specialists in complementary and alternative medicine.Conclusions: Modern scientifi c studies testify to the eff ectiveness, safety and necessity of using herbal preparations in thepathology of pregnancy and the postnatal period as one of the important components of medical pluralism. The specifi cs of their use must comply with the requirements of the DMR and be recommended on the basis of evidence- based medicine.

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“…On the other hand, because it has a defined chemical structure, it will interact with the body or with other medications, with results that, if not studied, are unpredictable for health (Grigoriu et al, 2021). Based on this premise, studies on plant extracts have been conducted to analyze the research criteria inherent to the different phases of scientific methodology.…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Systematic review on the anxiolytic and hypnotic effects of flower extracts in in vivo pre‐clinical studies published from 2010 to 2020

Meneses

Valdés

Garrido-Suárez³

et al. 2023

Phytotherapy Research

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Anxiety disorders are prevalent conditions in the world population, whose standard approaches include pharmacotherapy, psychotherapy, and combinations of these interventions. Different classes of psychopharmaceuticals are recommended as the first line of drugs to treat these disorders, which can have several adverse effects, treatment resistance, dependence, and drug–drug interactions making it necessary to search for new therapeutic agents. In particular, diazepam (DZP), a prototype drug from the group of benzodiazepines, has been commonly used and evaluated for its efficacy and safety in different anxiety disorders in clinical trials. DZP is also the most widely used reference standard in in vivo pharmacological assays of natural compounds. However, translating the results obtained in different rodent species and physiological anxiety tests instead of psychopathological animal models that can be of clinical application remains challenging. A systematic review of scientific articles published between 2010 and 2020 that included in vivo pre‐clinical tests to define the anxiolytic, sedative and/or hypnotic effect of flower extracts is proposed. PRISMA and Rayyan were used for the selection of studies using four databases (Pubmed, Scopus, Web of Science, and QInsight), using the keywords: “Animals,” “Anxiolytic,” “Diazepam,” “Elevated Plus Maze,” “Flower Extracts,” “Insomnia,” “In vivo,” “Mice,” “Open Field Test,” “Pre clinical” and “Sedative.” The characteristics of anxiety studies in animal models, other studies related to locomotor activity, and the hypnotic effect of the extracts were compiled. Twenty‐four articles were included, 21 of them performed the animal model of anxiety‐like behavior of the elevated plus maze, seven the open field test, and six the light–dark box test. The locomotor activity was evaluated in 10 studies after the administration of the extracts to the animals to define their sedative effect, where only one defined that the extract (Matricaria chamomilla) had a sedative effect. The plants declared with this type of activity were Achyranthes aspera, Alcea aucheri, Brassica nigra, Cananga odorata, Carthamus tinctorius, Chrysanthemum indicum, Citrus aurantium, Couroupita guianensis, Echium amoenum, Erythrina berteroana, Gardenia jasminoides, Hibiscus tilliaceus, Lavandula officinalis, Lawsonia inermis, Matricaria chamomilla, Melia azedarach, Nerium oleander, Passiflora incarnata, Plumeria rubra, Salix aegyptiaca, Syzygium aromaticum, Tagetes erecta, Tilia americana. Although this review showed that some flower extracts have an anxiolytic effect as effective as diazepam, their therapeutic utility in anxiety disorders remains to be extensively demonstrated. Hence, more reliable and predictive behavioral tests and appropriate strategies for the experimental designs are needed to obtain more conclusive evidence with clinical significance.

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Phytotherapy in obstetrics – therapeutic indications, limits, and dangers

Cited by 6 publications

References 28 publications

Complementary and Alternative Medicines Used by Individuals With Rheumatological Diseases to Cope With Sleeplessness

Complementary and Alternative Medicines Used by Individuals With Rheumatological Diseases to Cope With Sleeplessness

Characteristics of Phytotherapeutic Use During Pregnancy and in the Postnatal Period: Indications, Limitations, and Risks (Literature Review and Original Research)

Systematic review on the anxiolytic and hypnotic effects of flower extracts in in vivo pre‐clinical studies published from 2010 to 2020

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