Phytosterols: Beneficial Effects

Santas, Jonathan; Codony, R.; Rafecas, Magda

doi:10.1007/978-3-642-22144-6_149

Cited by 21 publications

(16 citation statements)

References 151 publications

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“…Furthermore, the phytosterols identified in all by-products have been reported to exert antidiabetic effects through the inhibition of nutrients absorption (Santas, Codony, & Rafecas, 2013).…”

Section: Proposed Compoundmentioning

confidence: 99%

Juice by-products as a source of dietary fibre and antioxidants and their effect on hepatic steatosis

Amaya-Cruz

Rodríguez-González

Pérez‐Ramírez

et al. 2015

Journal of Functional Foods

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Section: Proposed Compoundmentioning

confidence: 99%

Juice by-products as a source of dietary fibre and antioxidants and their effect on hepatic steatosis

Amaya-Cruz

Rodríguez-González

Pérez‐Ramírez

et al. 2015

Journal of Functional Foods

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“…Phytosterols (plant sterols) are structural analogs of cholesterol [28]. Several studies have shown that consumption of phytosterols reduces blood cholesterol, through which they reduce risk of cardiovascular diseases in diabetic and non-diabetic patients [29,30]. In addition, soybean oil is a major source of linoleic acid and linolenic acid [31].…”

Section: Discussionmentioning

confidence: 99%

Comparison of Canola and Soybean Oils on Serum Lipid and Glucose Profiles and Anthropometric Parameters in Overweight and Obese Type 2 Diabetes Mellitus Patients: A Randomized Clinical Trial

Shahraki

Rahati

Keykhaei

et al. 2021

Preprint

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Background No earlier human study compared influences of canola and soybean oils on patients with type 2 diabetes (T2D). Current study aimed to investigate effects of canola and soya oils on blood and anthropometric parameters in overweight and obese Iranian diabetic (II) patients. Methods A total of sixty-six T2D subjects were randomly allocated to three groups. Canola oil (CO; n 23, received 30g canola oil); Soya oil (SO; n 19, received 30g soya oil) and control group (n 24, their usual intake of dietary oils) for 8 weeks. Lipid and glycemic profiles as well as anthropometric indicators were evaluated before and after the intervention. Repeated-measures ANOVA was used to evaluate time×group interactions for the outcome variables followed by a t test (significance level, p < 0.05). Results After 8 weeks, serum total cholesterol (-21.3 and -36.4v. -2.2 mg/dl; P=0·007), low density lipoprotein (-6.6 and -15.9v. +3.0 mg/dl; P=0·013), fasting blood sugar (-39.6 and -30.5v. +11.7 mg/dl; P<0.001) significantly decreased and high density lipoprotein (+3.0 and +3.5v. +2.4 mg/dl; P=0.038) significantly increased in CO and SO groups compared with controls. Changes in lipid profiles were more considerable in the soybean oil group than the canola oil group. The mean changes of waist circumference (WC; −4.1 v. -1.4 and -1.3 cm; P=0·031) and weight (−3.1 v. -0.3 and +0.5 kg; P=0·048) significantly decreased in canola group comparing to the two other groups. Conclusions Current study showed that daily consumption of canola and soybean oil for 8 weeks improved serum levels of fasting blood sugar, total cholesterol, low density lipoprotein and high density lipoprotein in T2D patients. Changes were more considerable in those consumed soybean oil. Canola oil decreased central obesity indices (waist circumference and weight) in T2D patients. Further studies are needed to shed light on this issue. Trial registration: The trial registration number at irct.ir is IRCT2012062510110N1. Registered 23 July 2012. Retrospectively registered. https://fa.irct.ir/search/result?query=IRCT2012062510110N1

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“…The molecular similarities between phytosterols and human cholesterol enable phytosterols to successfully reduce serum cholesterol levels by preventing cholesterol absorption within the small intestine (Santas, Codony, & Rafecas, 2013). Phytosterols also possess anti-…”

Section: A C C E P T E D Mmentioning

confidence: 99%

Physical and interfacial characterization of phytosterols in oil-in-water triacylglycerol-based emulsions

et al. 2019

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of the phytosterol within the carrier matrix. Currently, there is a limited amount of knowledge on how phytosterols interact at oil-water interfaces, despite research indicating that these interfaces could promote the crystallization of phytosterols and thus decrease bioaccessibility.In order to fill this knowledge gap, this work expands upon a previously studied emulsion system for encapsulating phytosterols and addresses whether phytosterols can crystalize at an oil-in-water emulsion interface. Images from multiple microscopic techniques suggest interfacial phytosterol crystallization in 0.6% phytosterol-enriched emulsions, while interfacial tension results and calculated models showed that whey protein and phytosterols had a synergistic effect on interfacial tension. A deeper understanding of the interfacial behavior of phytosterols in emulsions can provide the functional food and pharmaceutical industry with the knowledge needed to design more bioaccessible phytosterol-enriched products.

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Phytosterols: Beneficial Effects

Cited by 21 publications

References 151 publications

Juice by-products as a source of dietary fibre and antioxidants and their effect on hepatic steatosis

Juice by-products as a source of dietary fibre and antioxidants and their effect on hepatic steatosis

Comparison of Canola and Soybean Oils on Serum Lipid and Glucose Profiles and Anthropometric Parameters in Overweight and Obese Type 2 Diabetes Mellitus Patients: A Randomized Clinical Trial

Physical and interfacial characterization of phytosterols in oil-in-water triacylglycerol-based emulsions

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