Phytomedicines for Candida-associated denture stomatitis

Casaroto, Ana Regina; Lara, Vanessa Soares

doi:10.1016/j.fitote.2009.12.003

Cited by 59 publications

(71 citation statements)

References 60 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…5 According to a classification proposed by Newton in 1962, DS is divided into three types based on the clinical features. 6,7 Despite its high prevalence rate, the aetiology of DS is not fully understood 8 and is also somewhat controversial; however, researchers believe that the entity has a complex and multifactorial pathogenesis. 9 Infection by Candida albicans has been surmised to be the main aetiological agent and it has been correlated with the incidence of DS in various studies.…”

mentioning

confidence: 99%

“…1 Various studies on the aetiology of DS have indicated that diabetes mellitus and smoking might have a role in inducing the lesion. 5,7,16 A review of 15 studies, published in the years 1989-2011 in various parts of the world, on the factors involved in the pathogenesis of DS, showed that the most significant factors are continuous and overnight denture-wearing; [3][4][5][8][9][10][11] poor denture hygiene; 2,4,12,[17][18][19] smoking; [14][15][16]20,21 denture age and poor denture manufacturing techniques; 22,23 low serum levels of vitamin A; young age, and the number of visits to the dental surgery. 7 Nimri showed that nocturnal denture-wearing habits, deficient oral and denture hygiene, and cigarette smoking were all important predisposing factors to DS; however, none of these factors was the sole cause of mucosal inflammation.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Risk Factors Associated with Denture Stomatitis in Healthy Subjects Attending a Dental School in Southeast Iran

Navabi¹,

Gholamhoseinian²,

Baghaei³

et al. 2013

SQUMJ

View full text Add to dashboard Cite

abstract:Objectives: There is scant information regarding the multifactorial aetiology of denture stomatitis (DS) in the world and, despite its frequency, associated factors are not completely understood. The aim of this study was to investigate the risk factors that may be associated with this lesion. Methods: A total of 70 edentulous patients, all wearing removable dentures, were divided into two groups. The test group comprised 43 patients with DS and the control group comprised 27 subjects with clinically healthy palatal mucosa. A thorough history-taking and physical examination were carried out; the subjects also answered a questionnaire. The serum level of vitamin A for each subject was assayed from a blood sample taken after the examination. Results: This study showed a significant relationship between the incidence of DS and three major factors: denture age (in terms of years), the practitioner manufacturing the dentures (general dental practitioner versus dental hygienist), and the nightlong wearing of dentures. Also, the vitamin A serum level was low in 94.29% of all subjects (cases and controls). Conclusion: Although many predisposing conditions were related to this situation, the most important risk factor was the continuous use of the dentures. Keywords Application to Patient Care-The results of this study will help in increasing awareness of DS for dentists.-Dentists can help prevent this condition by instructing patients to take their dentures out for 6-8 hrs each day.-Mechanical plaque control and appropriate denture-wearing habits are the most important measures in preventing and treating the disease.

show abstract

mentioning

confidence: 99%

mentioning

confidence: 99%

Risk Factors Associated with Denture Stomatitis in Healthy Subjects Attending a Dental School in Southeast Iran

Navabi¹,

Gholamhoseinian²,

Baghaei³

et al. 2013

SQUMJ

View full text Add to dashboard Cite

show abstract

“…C. albicans is responsible for the majority of infections in humans. Also medicinal plants are used in different disease treatments and they are popular all over the world [7]. Different studies showed anti-fungal activity of medicinal plants against C. albicans [1].…”

Section: Discussionmentioning

confidence: 99%

“…According to the literature, the investigation for natural products to be used against Candida species increased significantly in the last 10 years examining approximately 258 plant species from 94 families [2,7]. Wild melon (Cucumis melo L.), belongs to the cucurbitaceae family, it is an annual plant, herbaceous, prostrates, creeping and its fruit is as large as 2 -40 × 8 -24 mm, it is ellipsoid and yellow and dark green veined with bitter pulps [8].…”

Section: Introductionmentioning

confidence: 99%

In vitro Antifungal Activity of Cucumis melo on Candida albicans

Azizi

Rouhi

Yahyayi

2015

Zahedan J Res Med Sci

View full text Add to dashboard Cite

Background: With respect to the emergence of susceptibility of some fungi to antifungal agents, making use of medicinal plants is progressing. Objectives: The aim of this study was to verify the anti-fungal characteristics of mature and immature Cucumis melo fruit on Candida albicans. Materials and Methods: In this descriptive study, antifungal activity of aqueous, ethnolic and methanolic extracts of C. melo fruits were tested on C. albicans; also results were obtained by disc and well diffusion methods. Results: Minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) of mature C. melo fruit methanolic extract were 25 × 10 3 and 5 × 10 4 μg/mL, respectively. MIC and MFC of immature fruit methanolic extract was 25 × 10 3 . For mature fruit ethanolic extract, MIC and MFC was 25 × 10 3 μg/mL and for immature C. melo fruit ethanolic extract MIC was 25 × 10 3 and MFC was 5 × 10 4 μg/mL. Gas chromatography/mass spectrometry (GC/MS) results showed that hexadecanoic acid was present in all of the extracts. The maximum size of inhibition zone for mature and immature methanolic extact in the disc method was 12 mm and in well method were 15 and 17 mm, respectively. In the disc method, for mature and immature ethanolic extracts maximum size of inhibition zones were 35 and 36 mm and in the well method, maximum size of inhibition zones for mature and immature ethanolic extracts were 28 and 15 mm, respectively. Conclusions: These results indicated that C. melo extracts contain compounds with therapeutic potential and anti-fungal characteristics against C. albicans.

show abstract

“…Thus, the use of phytotherapic as denture cleanser could be an alternative method to overcome this issue. In this context, the mechanical properties assessment is important since higher Ra could result in higher biofilm formation, consequently increasing the potential to develop biofilm-based diseases and it is usually not tested in microbiological studies 6,13 . In this study, Ra was not affected by the treatments, although there are reports in the literature showing damage caused by NaOCl 14 .…”

Section: Discussionmentioning

confidence: 99%