Phytohemagglutinin and Hematopoietic Stem Cells in the Mouse

Scaro, J L; Carrera, M; Teruel, J.E.; Tombolesi, Raquel Alvarez Prado de

doi:10.1159/000208587

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1973

1980

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Cited by 4 publications

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“…The effects of FS on the number of HSC was assessed by measuring the number of colony forming units (CFU) per 105 spleen cells by the transplant method as previously described [7], Prospective cell donors were either normal or fasted mice. Deprivation of food in the latter was started on day 1 with free access to water.…”

Section: Methodsmentioning

confidence: 99%

Erythropoietic Changes Effected by Foreign Serum in the Mouse

Scaro¹,

Miranda²,

Martín³

et al. 1980

Acta Haematol

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Injection of foreign serum into mice increases erythrocyte formation as evaluated by ferrokinetics studies. When erythropoiesis is depressed either by fasting or plethora, the wave of erythropoiesis that follows a transient increase of endogenous erythropoietin is clearly enhanced by pretreatment of the recipients with foreign serum. The response includes a restoration of the responsiveness of the spleen of fasted mice to endogenous erythropoietin stimulation. These changes seem related to an effect of foreign serum on the transition of primitive hematopoietic progenitors into erythroid-committed progenitors.

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Section: Methodsmentioning

confidence: 99%